Effect of ethanol and fructose on plasma uridine and purine bases

Metabolism: Clinical and Experimental
T YamamotoK Higashino

Abstract

To determine whether both ethanol and fructose increase the plasma concentration of uridine, we administered ethanol (0.6 g/kg) or fructose (1.0 g/kg) to seven normal subjects. Both ethanol and fructose increased the plasma concentration of uridine together with an increase in the plasma concentration of oxypurines, whereas fructose also increased the plasma concentration of uric acid, but ethanol did not. In ethanol ingestion and fructose infusion, an increase in the plasma concentration of purine bases correlated with that of uridine. These results strongly suggest that an increase in the plasma concentration of uridine is ascribable to increased pyrimidine degradation following purine degradation increased by ethanol and fructose.

Citations

Dec 4, 2014·Physiological Research·W DudzinskaM Janiak
Jan 31, 2002·Journal of Endocrinological Investigation·A CavarapeA Ceriello
Aug 15, 2017·Purinergic Signalling·Faming TianChristopher H E Imray
Oct 3, 2003·The American Journal of Clinical Nutrition·Li-Ching LyuChing-Lan Chen
Oct 27, 2006·Nucleosides, Nucleotides & Nucleic Acids·Y MoriwakiT Yamamoto
Jul 30, 2008·Critical Reviews in Food Science and Nutrition·M S Fernandez-PanchonM C Garcia-Parrilla
Jun 15, 2010·Nucleosides, Nucleotides & Nucleic Acids·Tetsuya YamamotoYuji Moriwaki
Jul 5, 2008·Nucleosides, Nucleotides & Nucleic Acids·Taku InokuchiTetsuya Yamamoto
Jun 22, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Tetsuya YamamotoYuji Moriwaki
Dec 30, 1998·Journal of Chromatography. B, Biomedical Sciences and Applications·T YamamotoM Shioda
Jan 24, 1998·Metabolism: Clinical and Experimental·T YamamotoK Higashino
Jun 17, 1998·Metabolism: Clinical and Experimental·T YamamotoK Higashino
Aug 26, 1998·Metabolism: Clinical and Experimental·T YamamotoK Higashino
Aug 25, 1999·Metabolism: Clinical and Experimental·T YamamotoK Higashino
Jun 7, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Tetsuya YamamotoSumio Takahashi
May 3, 2018·Journal of Agricultural and Food Chemistry·Po-Sheng WangWen-Harn Pan
Jul 3, 2010·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Noriko YamaokaKiyoko Kaneko

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.