Effect of ethanol and some alcoholic beverages on gastric emptying in humans

Scandinavian Journal of Gastroenterology
A FrankeM V Singer

Abstract

There is a paucity of detailed and controlled studies on the action of ethanol and alcoholic beverages on gastric emptying in humans. This study was designed to compare the effect of beer, red wine, whisky and their comparable pure ethanol solutions on gastric emptying in a controlled and randomized investigation. On separate days, 10 healthy, fasted subjects received the following solutions, in random order, through a gastric tube: 500 mL beer, red wine, comparable pure ethanol solutions (4% and 10% v/v), glucose (5.5% and 11.4% w/v) and water, 125 mL whisky and 40% (v/v) ethanol (both followed by 125 mL water) and 250 mL water. Gastric emptying of the test solutions was assessed using ultrasonography of the antrum. As measured by ultrasonography of the antrum, half emptying times of the ethanol solutions (4%, 10% and 40% v/v) were significantly (P < 0.05) longer (22.6 +/- 4.8, 22.7 +/- 4.3 and 27.8 +/- 3.3 min, respectively, n=10) than those of water (14.6 +/- 1.9 min (500 mL) and 13.2 +/- 1.7 min (250 mL), respectively). The half emptying times of beer (39.3 +/- 4.3 min) and red wine (72.6 +/- 7.6 min) were significantly longer than those of the corresponding ethanol concentrations, whereas whisky was emptied at nearly the s...Continue Reading

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Citations

Apr 2, 2009·Pharmaceutical Research·Igor LocatelliMarija Bogataj
Dec 1, 2011·American Journal of Veterinary Research·Abdullah Ehsani-KheradgerdiWalter Grünberg
Sep 21, 2007·Drug Development and Industrial Pharmacy·Malcolm WaldenGeoffrey T Tucker
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May 15, 2021·Inflammatory Bowel Diseases·Bradley A WhiteSunanda Kane
Dec 3, 2017·Best Practice & Research. Clinical Gastroenterology·Gabriele Capurso, Edith Lahner

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