PMID: 3767274Jul 1, 1986Paper

Effect of ethanol on erythrocyte acetylcholinesterase activity

Annals of Clinical Biochemistry
N A Haboubi, D I Thurnham

Abstract

Erythrocyte acetylcholinesterase (AchE) activity was measured in the blood of 36 alcoholic subjects and 41 healthy volunteers. The mean activity in the alcoholics was significantly lower than that in the control subjects. In vitro experiments showed that ethanol inhibited the AchE activity immediately and in proportion to the concentration of ethanol used. Incubation times up to 6 h did not increase the inhibition significantly. Incubation of normal red cells with ethanol for 15 h, followed by washing, showed also that AchE activity was inhibited by the previous exposure to ethanol and that washing did not reduce the inhibitory effect. The possibility is considered that depressed erythrocyte AchE activity may be an early indication of potential disturbances of the autonomic nervous system. The importance of reporting ethanol intake in patients with organophosphorus poisoning is stressed.

References

Jan 1, 1976·International Review of Neurobiology·A K Rawat
Nov 1, 1978·Proceedings of the Society for Experimental Biology and Medicine·T H ParkerS Schenker
Jan 1, 1967·Canadian Journal of Physiology and Pharmacology·H KalantM A Mahon
Mar 1, 1983·Acta Neurologica Scandinavica·B Melgaard
Nov 1, 1983·Drug and Alcohol Dependence·T C ChanM C Sutter
Jan 1, 1981·Advances in Clinical Chemistry·S S BrownC L Woronick
Dec 1, 1982·Drug and Alcohol Dependence·A NordbergB Winblad
Jan 15, 1980·Biochemical and Biophysical Research Communications·S K Jain, P Hochstein
May 1, 1980·Archives of Biochemistry and Biophysics·S K Jain, P Hochstein
Jul 1, 1961·Biochemical Pharmacology·G L ELLMANR M FEATHER-STONE

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Citations

Apr 20, 2006·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Annetta WatsonVeronique Hauschild
Apr 12, 2005·Archives of Biochemistry and Biophysics·Zoran ArsovMilan Schara
Jul 1, 1988·Annals of Clinical Biochemistry·M H AbernethyE G Stephenson
Jul 1, 1988·Annals of Clinical Biochemistry·S W Mann, A Green

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