PMID: 9171969May 1, 1997Paper

Effect of exercise training and detraining on gas exchange kinetics in patients with chronic obstructive pulmonary disease

Clinical Physiology
T OtsukaJ Yoshikawa

Abstract

Symptom-limited incremental exercise tests are used to estimate the training effect on patients with chronic obstructive pulmonary disease (COPD). However, there is a need for objective parameters for measurement on submaximal exercise testing. The purpose of this study was to assess the usefulness of measurement of oxygen uptake (VO2) kinetics during a constant work rate exercise test of patients with COPD after exercise training. Eleven patients with COPD performed exercise tests before and after cycle ergometer training on 3 days per week for 8 weeks; they then went without training for 5 months and performed the same tests. They performed an incremental exercise test to symptom-limited maximum and a constant work rate exercise test for 6 min on a cycle ergometer. The time constant of VO2 during the onset of constant work rate exercise was significantly decreased (from 63.5 +/- 7.8 s to 53.2 +/- 8.0 s) after exercise training (P = 0.021), but was significantly increased (to 73.4 +/- 14.9 s) after 5 months without training (P = 0.001). The oxygen pulse at steady state during constant work rate exercise testing was significantly increased after exercise training but decreased 5 months later. The change in blood lactate from re...Continue Reading

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Citations

Feb 29, 2008·Bulletin of Mathematical Biology·J R StirlingV Billat
Apr 9, 2004·American Journal of Respiratory and Critical Care Medicine·Hean-Yee OngMarshall S Riley
Nov 17, 2015·Expert Review of Respiratory Medicine·Baruch VainshelboimMordechai Reuven Kramer
Mar 23, 2011·Respiratory Physiology & Neurobiology·Simon MarwoodPeter Calverley
Mar 25, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Naoki IjiriKazuto Hirata
May 15, 2002·Clinical Physiology and Functional Imaging·Pelagia KoufakiPatrick F Naish
Apr 23, 2010·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Don HayesHubert O Ballard
Aug 8, 2002·Medicine and Science in Sports and Exercise·Pelagia KoufakiThomas H Mercer
Jun 1, 2006·Disability and Rehabilitation. Assistive Technology·Yoshiyuki FukuokaMasahiro Itoh
Jan 5, 2021·Medicine and Science in Sports and Exercise·Joren BuekersMartijn A Spruit

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