PMID: 376377Mar 1, 1979Paper

Effect of fasting on the release of insulin and somatostatin from perifused islets of Langerhans

Diabetes
P SchauderH Frerichs

Abstract

Release of somatostatin and insulin from perifused islets of fasted and control rats was compared. After a fasting period of 48 h glucose-induced insulin release but not somatostatin release was diminished. Islets from fasted rats released significantly more somatostatin in the presence of 3.3 mM glucose than islets from controls. Simultaneously, the somatostatin content of isolated islets from fasting rats was significantly decreased. The results indicate that the low secretory activity of islet B cells in the fasting state is associated with a high secretory activity of islet D cells.

Citations

Mar 1, 1986·Regulatory Peptides·H SchwartingR Arnold
Nov 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·S EfendićR Luft
Jul 1, 1993·Scandinavian Journal of Gastroenterology·O OktedalenJ J Holst
Apr 1, 2008·Molecular and Cellular Endocrinology·Mathias Z Strowski, Allan D Blake
Aug 25, 2004·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Mark A Sheridan, Jeffrey D Kittilson
Jun 1, 1983·Metabolism: Clinical and Experimental·C A Longano, H P Fletcher
May 28, 2014·Birth Defects Research. Part C, Embryo Today : Reviews·Philip diIorioAgata Jurczyk

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