Effect of feeding regime on the metabolism of ochratoxin A during the in vitro incubation in buffered rumen fluid from cows

Archiv für Tierernährung
H M MüllerH Steingass

Abstract

Pure ochratoxin A (OA) was added to buffered rumen fluid collected from two fistulated cows and incubated under anaerobic conditions. Both animals were fed six diets containing grass, grass silage or hay, and two different amounts of concentrate consisting of barley and soybean meal. Four incubations per animal and diet were carried out at consecutive days. The concentration of OA declined exponentially to a very low or non-detectable level under all conditions examined, with half-lives at 0.51 to 2.76 h. The disappearance of OA was accompanied by the appearance of ochratoxin alpha (O alpha) with an average amount of O alpha formed relative to the disappearance of OA near 100%, independent of diet and animal. Based on four incubations per animal and diet the rate of OA disappearance was affected (P < 0.1) by the origin of rumen fluid from two animals, as well as by the type of basic component and amount of concentrate in the diet, with interactions between these factors. The disappearance of OA mostly was accelerated (P < 0.1) by replacing grass silage or hay by fresh grass and by increasing the content of concentrate from 10 to 50% of dry matter. It is concluded that the capacity of the rumen to detoxify OA is not limited by t...Continue Reading

References

Sep 1, 1976·Applied and Environmental Microbiology·K HultS Gatenbeck
Jul 1, 1988·Journal of Animal Science·O SreemannarayanaD Abramson
Mar 1, 1973·The British Journal of Nutrition·M AbeF Kumeno

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Citations

Mar 1, 2005·Mycotoxin Research·A MacriM V Morar
Feb 21, 2008·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Johanna Fink-Gremmels
Jul 1, 2010·Toxins·Gianni BattaconeGiuseppe Pulina
Jul 13, 2018·Frontiers in Microbiology·Wenying ChenXiao L Shen

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