Effect of feline skin specimen preparation on postexcision and postfixation tissue shrinkage

Journal of Feline Medicine and Surgery
Marije RisseladaEmily Griffith

Abstract

This study was performed to assess skin-muscle-fascia specimen shrinkage and donor site changes, and to compare three techniques of specimen preparation for their effect on specimen shrinkage postexcision and after formalin fixation in feline cadaveric specimens. Fifteen fresh feline cadavers were used for this study. Gelatin spheres were implanted in paired thoracic subcutaneous pockets and subsequently excised with 30 mm lateral margins and a fascial plane as the deep margin. Skin and fascia were either left unsutured, sutured together using four simple interrupted quadrant sutures ('four-quadrant-sutured') or sutured together in a continuous pattern ('circumferentially sutured'). Specimens were measured for tumor-free margins on the excised and fixed specimens. The donor site defect was assessed for enlargement after specimen excision. Statistical analyses were performed to assess the donor site enlargement, and the influence of preparation technique on margin size, with significance set at P <0.05. The closest skin margins on the excised and fixed specimens were significantly smaller than the planned 30 mm margins; however, no significant difference was found between postexcision and postfixation specimens. No significant d...Continue Reading

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Citations

Feb 13, 2018·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Patti K KiserDuncan S Russell

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