Effect of ferric-carboxy maltose on oxygen kinetics and functional status in heart failure patients with iron deficiency

Future Science OA
Sandip DhootVarshil Mehta

Abstract

There is a very high prevalence of iron deficiency anemia in patients with systolic heart failure. The present study is a prospective, parallel, 1:1 randomized controlled trial of intravenous ferric-carboxy maltose compared with standard of care in patients with heart failure. A total of 70 patients who presented to us with symptomatic chronic heart failure were included and randomly assigned to either groups (35 per group). Post 12 weeks, there were improvements noticed in peak VO2, New York Heart Association functional classification, 6-min walk test distance covered and reduction in Minnesota Living with Heart Failure Questionnaire score in the ferric-carboxy maltose as compared with standard of care group. However, no improvement in ejection fraction was noticed.

References

Jul 2, 2002·American Journal of Respiratory and Critical Care Medicine·UNKNOWN ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories
Oct 1, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ajay SinghLouis Brenner
Nov 19, 2009·The New England Journal of Medicine·Stefan D AnkerUNKNOWN FAIR-HF Trial Investigators
Feb 3, 2015·European Journal of Heart Failure·Theresa McDonagh, Iain C Macdougall
Jun 23, 2015·International Journal of Molecular Sciences·Donald S SilverbergDoron Schwartz
Jul 14, 2017·Circulation·Dirk J van VeldhuisenUNKNOWN EFFECT-HF Investigators
Sep 12, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Rajiv RamasawmyDaniel A Herzka

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Citations

Apr 3, 2021·Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace·Edoardo SciattiAndrea Di Lenarda

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Software Mentioned

HF
CONFIRM
EFFECT
FERRIC
FAIR
SPSS

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