Effect of Fluoride Varnish and Dentifrices and Its Combination on Deciduous Enamel Demineralization: An In vitro Study

Journal of Pharmacy & Bioallied Sciences
Allama PrabhuMallikarjuna Ragher

Abstract

Dental caries remains the most important dental health problem in developing countries. Application of varnish on tooth surfaces is shown to promote the uptake of firmly bound fluoride by enamel, which is considered important. Along with the incorporation of fluoride into the crystalline lattice, there is formation of calcium fluoride compounds on enamel. Seventy deciduous canines were covered with nail polish. A window measuring 4 mm × 4 mm was left on their buccal surface, These were randomly assigned to seven groups (n = 6): S: sound enamel not subjected to any regimen or treatment; N: negative control, subjected to the pH-cycling regimen without any treatment; D1 and D2: subjected to the pH-cycling regimen and treated two times daily with 1100 and 500 ppm F dentifrice, respectively; VF: fluoride varnish (subjected to F-varnish before and in the middle of the pH-cycling regimen); and VF + D1 and VF + D2. After a period of 10 days, sectioning of teeth was done, and enamel demineralization was measured. The combination of dentifrice and varnish (groups VF + D1 and VF + D2) significantly reduced demineralization compared with the N group at all distances evaluated (P < 0.05), but the combination did not differ from the dentifri...Continue Reading

References

Apr 1, 1982·Community Dentistry and Oral Epidemiology·K GrodzkaG Frostell
Jul 27, 2004·Brazilian Oral Research·Silvia José Chedid, Jaime Aparecido Cury
Oct 7, 2004·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Liisa Seppä
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Oct 28, 2011·Brazilian Oral Research·Alessandra GattiDaniela Prócida Raggio
Jul 9, 2013·Journal of Conservative Dentistry : JCD·Priyadarshini ShRaghu Srinivasan

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