Effect of Foeniculum vulgare Mill. (fennel) on menopausal symptoms in postmenopausal women: a randomized, triple-blind, placebo-controlled trial

Menopause : the Journal of the North American Menopause Society
Fatemeh RahimikianAbbas Mehran

Abstract

Preliminary data suggest that Foeniculum vulgare (fennel) can be an effective treatment for menopausal symptoms. This trial was designed to assess the efficacy of fennel in the management of menopausal symptoms in postmenopausal women. In this triple-blind, placebo-controlled trial, 90 postmenopausal women aged 45 to 60 years in Tehran were randomly assigned to treatment (n = 45) or placebo (n = 45) groups. The participants received 8 weeks of treatment with soft capsules containing 100 mg fennel or a placebo (2 per day for each group). The participants were followed for 2 weeks postintervention to assess the continuance of the effect of intervention. The Menopause Rating Scale (MRS) questionnaire was used to assess changes in menopausal symptoms at baseline and at 4, 8, and 10 weeks after onset of intervention. The groups recorded similar mean scores on the MRS questionnaire before intervention. After intervention, the treatment group showed a significant decrease in the mean MRS score. The results of the Friedman test showed significant differences between the mean score at baseline and those at 4, 8, and 10 weeks after onset of intervention in the treatment group (P < 0.001), whereas there were no significant differences in ...Continue Reading

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Citations

May 14, 2019·Journal of Menopausal Medicine·Mohaddese Mahboubi
Aug 17, 2020·Menopause : the Journal of the North American Menopause Society·Parvin GhaffariNazafarin Hosseini
Nov 23, 2020·Complementary Therapies in Medicine·Zahra Sheikhi-MobarakehGhazaleh Heydarirad
Oct 29, 2020·Menopause : the Journal of the North American Menopause Society·Parvin GhaffariNazafarin Hosseini
Mar 13, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Sousan HafiziMalihe Tabarrai
Mar 17, 2021·Complementary Therapies in Clinical Practice·Hye Won LeeMyeong Soo Lee

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