Effect of fractional blood flow on plasma skimming in the microvasculature

Physical Review. E
Jiho YangTae-Rin Lee

Abstract

Although redistribution of red blood cells at bifurcated vessels is highly dependent on flow rate, it is still challenging to quantitatively express the dependence of flow rate in plasma skimming due to nonlinear cellular interactions. We suggest a plasma skimming model that can involve the effect of fractional blood flow at each bifurcation point. To validate the model, it is compared with in vivo data at single bifurcation points, as well as microvascular network systems. In the simulation results, the exponential decay of the plasma skimming parameter M along fractional flow rate shows the best performance in both cases.

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Sep 23, 2016·Biomechanics and Modeling in Mechanobiology·Tae-Rin LeeJiho Yang

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Citations

Mar 10, 2018·International Journal for Numerical Methods in Biomedical Engineering·Tae-Rin LeeDo Wan Kim
Nov 14, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Tejapratap BolluPeter C Doerschuk
Oct 29, 2020·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Daisuke SakotaOsamu Maruyama

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