Effect of general anaesthesia on intraocular pressure in paediatric patients: a systematic review.

Eye
Sukhumal ThanapaisalYing Han

Abstract

Assessment of the impact of general anaesthetic agents on intraocular pressure (IOP) in children via systematic review. Pubmed, Embase, and CENTRAL databases were systematically searched to identify randomised controlled trials, prospective, and interventional studies. The search included all studies through October 5, 2018 with no date or language restrictions. A linear mixed-effects regression analysis was performed to study the change in IOP after general anaesthesia (GA). The strategy identified 518 studies that met search criteria. Six studies (531 eyes) were included for quantitative synthesis. Seven categories of mixed and non-mixed induction and maintenance agents were compared. When assessing all agents utilising a model of mean IOP as a function of time, IOP decreased after induction phase at a rate of -0.59 ± 0.19 mmHg/min (P value = 0.006). This systematic review showed that most anaesthetic agents significantly decrease IOP over time after the induction phase of general anaesthesia in children. An understanding of the effects of GA on IOP is critical for those performing paediatric ophthalmic examinations under anaesthesia.

References

Dec 1, 1995·Anesthesia and Analgesia·T J EbertM Muzi
Aug 11, 2000·Paediatric Drugs·K L GoaC M Spencer
Feb 28, 2001·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·T J EbertJ A Barney
Aug 19, 2006·Journal of Pediatric Ophthalmology and Strabismus·N G NagdeveS S Pandav
Feb 24, 2007·American Journal of Ophthalmology·Dana BlumbergHarry Quigley
Jun 17, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Julia LasseckWolf Alexander Lagrèze
Jun 12, 2009·Journal français d'ophtalmologie·H Bresson-Dumont
Sep 2, 2010·The British Journal of Ophthalmology·Isabel Oberacher-VeltenBirgit Lorenz
Dec 16, 2011·The American Journal of Emergency Medicine·Patrick C DraynaDonald H Arnold
Sep 27, 2012·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Sarah M HalsteadGenie E Roosevelt
Mar 4, 2014·Annals of Emergency Medicine·Shernaz WadiaMichelle Stevenson
May 31, 2014·Investigative Ophthalmology & Visual Science·Wen Jun JiangJost B Jonas
Jul 6, 2016·Paediatric Anaesthesia·Julia TermühlenVerena Prokosch
Nov 23, 2016·Current Opinion in Ophthalmology·Annette Giangiacomo, Allen Beck
Apr 26, 2017·Survey of Ophthalmology·Mikel MikhailAlex V Levin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.