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Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis

bioRxiv

Dec 10, 2013

J DembowyJames R Woodgett

Abstract

Many components of Wnt/β-catenin signaling pathway have critical functions in mammary gland development and tumor formation, yet the contribution of glycogen synthase kinase-3 (GSK-3α and GSK-3β) to mammopoiesis and oncogenesis is unclear. Here, we report that WAP-Cre-mediated deletion ...read more

Mentioned in this Paper

WFDC12 gene
Gene Deletion Abnormality
Glycogen Synthase Kinases
Adenosquamous Carcinoma
Deletion Mutation
Ctnnb protein, zebrafish
Catenins
Biochemical Pathway
glycogen synthase kinase 3 beta
Glycogen Synthase Kinase 3
7
11
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Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis

bioRxiv

Dec 10, 2013

J DembowyJames R Woodgett

PMID: 990001321

DOI: 10.1101/001321

Abstract

Many components of Wnt/β-catenin signaling pathway have critical functions in mammary gland development and tumor formation, yet the contribution of glycogen synthase kinase-3 (GSK-3α and GSK-3β) to mammopoiesis and oncogenesis is unclear. Here, we report that WAP-Cre-mediated deletion ...read more

Mentioned in this Paper

WFDC12 gene
Gene Deletion Abnormality
Glycogen Synthase Kinases
Adenosquamous Carcinoma
Deletion Mutation
Ctnnb protein, zebrafish
Catenins
Biochemical Pathway
glycogen synthase kinase 3 beta
Glycogen Synthase Kinase 3
7
11

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