PMID: 66569Apr 9, 1977

Effect of granulocytic chalone on acute myeloid leukaemia in man. A follow-up study

J A VilpoW A Jones


Non-pyrogenic preparations of granulocytic chalone have been administered to patient with acute myeloid leukaemia (A.M.L.) who had relapsed after chalone-induced complete remission of the disease. Another regression of the leukaemia was obtained. Normal and leukaemic granulocytes were inhibited without effect on other cell types. Survival was prolonged in 4 other patients with A.M.L. Further investigations are needed to elucidate the therapeutic role of granulocytic chalone.


Jun 7, 1969·Nature·T Rytömaa, K Kiviniemi


Nov 1, 1982·Biulleten' eksperimental'noĭ biologii i meditsiny·P D GodorozhaG B Pliss
Mar 1, 1979·Mechanisms of Ageing and Development·J C Houck
Mar 1, 1979·Mechanisms of Ageing and Development·T Rytömaa, H Toivonen
Jan 1, 1982·Pharmacology & Therapeutics·A M AttallahJ C Petricciani
Jan 18, 1979·Nature·M J Cline, D W Golde
Sep 1, 1981·Biulleten' eksperimental'noĭ biologii i meditsiny·P D GodorozhaG B Pliss
Dec 12, 2017·Cell Proliferation·T Rytömaa, K Grip-Rytömaa

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