Abstract
The effect of head-upright tilting on the rate of cerebral autoregulation was studied in 12 healthy volunteers (nine men and three women; age range 20-36 years). The dynamics of cerebral autoregulation was determined from the rate of change in cerebral resistance (RoR) during a drop in arterial blood pressure induced by rapid deflation of a 3-min ischaemic thigh cuff and from the ratio of changes in cerebral blood flow and arterial blood pressure (CAI) during the recovery period after the drop in arterial blood pressure. The test was performed supine and with 40 degrees head-up tilt (40 degrees HUT). Middle cerebral artery mean blood flow velocity was measured by transcranial Doppler simultaneously with peripheral arterial blood pressure using Finapres. The thigh cuff deflation induced a larger drop in arterial pressure during 40 degrees HUT [median -28% (25 percentile -36, 75 percentile -19)] than in the supine position [-16% (-23, -15)] (P < 0.01) and in cerebral resistance [supine: -12% (-15, -6); 40 degrees HUT: -15% (-20, -12); P < 0.05]. There was no significant change in RoR [15% s-1 (12, 15)] and CAI [1.9 (1.5, 3.1)] measured supine and during 40 degrees HUT [RoR: 13% s-1 (12, 15); CAI: 1.3 (0.99, 1.9)]. During the drop...Continue Reading
References
Sep 1, 1979·Medical & Biological Engineering & Computing·A E BunnJ C Vermaak
Jun 1, 1992·Journal of Neurosurgery·C A GillerD J Borchers
Jul 1, 1992·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·G Florence, J Seylaz
Jan 1, 1992·Stroke; a Journal of Cerebral Circulation·A DahlH Nornes
Sep 1, 1991·Stroke; a Journal of Cerebral Circulation·R AaslidK F Lindegaard
Sep 1, 1990·Neurosurgery·C A Giller
Jan 1, 1989·Stroke; a Journal of Cerebral Circulation·R AaslidH Nornes
Jan 1, 1989·Stroke; a Journal of Cerebral Circulation·H A Kontos
Nov 1, 1987·Stroke; a Journal of Cerebral Circulation·K F LindegaardH Nornes
Apr 1, 1974·Circulation Research·S StrandgaardA M Harper
Oct 1, 1995·Stroke; a Journal of Cerebral Circulation·R L BondarM L Riedesel
Oct 1, 1995·Stroke; a Journal of Cerebral Circulation·R R DiehlP Berlit
Aug 1, 1995·Stroke; a Journal of Cerebral Circulation·F P TiecksD W Newell
May 1, 1995·Stroke; a Journal of Cerebral Circulation·A A BirchG Neil-Dwyer
Jun 1, 1995·Stroke; a Journal of Cerebral Circulation·F P TiecksD W Newell
Apr 1, 1994·Stroke; a Journal of Cerebral Circulation·D W NewellH R Winn
Sep 1, 1994·Stroke; a Journal of Cerebral Circulation·A LagiL Colzi
Oct 1, 1994·Stroke; a Journal of Cerebral Circulation·F S LarsenG M Knudsen
May 1, 1993·Neurosurgery·C A GillerW Krippner
Oct 1, 1996·Journal of Neurosurgical Anesthesiology·T S MaybergE Visco
Citations
Feb 14, 2009·European Journal of Applied Physiology·James HearnDavid George Behm
Apr 17, 2009·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Ronney B Panerai
Dec 29, 2013·BioMed Research International·David K KungDavid M Hasan
Sep 3, 2010·Acta Neurologica Scandinavica·J GierthmühlenG Wasner
Apr 6, 1999·The American Journal of Cardiology·G LeftheriotisJ L Saumet
Jun 21, 2014·Journal of the American Heart Association·Maw Pin TanSteve W Parry
Oct 29, 2005·Stroke; a Journal of Cerebral Circulation·Rogier V ImminkJohannes J van Lieshout
Aug 22, 2001·Circulation·B J CareyJ F Potter
Feb 9, 2018·Physiological Reports·Man Y LamRonney B Panerai
Nov 25, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J M SerradorA W Gelb
Jan 21, 2006·Journal of Applied Physiology·Hong GuoXiangrong Shi