Effect of health information exchange on recognition of medication discrepancies is interrupted when data charges are introduced: results of a cluster-randomized controlled trial.

Journal of the American Medical Informatics Association : JAMIA
Kenneth S BoockvarWilliam Hung

Abstract

To determine the effect of health information exchange (HIE) on medication prescribing for hospital inpatients in a cluster-randomized controlled trial, and to examine the prescribing effect of availability of information from a large pharmacy insurance plan in a natural experiment. Patients admitted to an urban hospital received structured medication reconciliation by an intervention pharmacist with (intervention) or without (control) access to a regional HIE. The HIE contained prescribing information from the largest hospitals and pharmacy insurance plan in the region for the first 10 months of the study, but only from the hospitals for the last 21 months, when data charges were imposed by the insurance plan. The primary endpoint was discrepancies between preadmission and inpatient medication regimens, and secondary endpoints included adverse drug events (ADEs) and proportions of rectified discrepancies. Overall, 186 and 195 patients were assigned to intervention and control, respectively. Patients were 60 years old on average and took a mean of 7 medications before admission. There was no difference between intervention and control in number of risk-weighted discrepancies (6.4 vs 5.8, P = .452), discrepancy-associated ADEs (...Continue Reading

References

Oct 1, 1992·Journal of Clinical Epidemiology·J T HanlonJ R Feussner
Aug 1, 1981·Clinical Pharmacology and Therapeutics·C A NaranjoD J Greenblatt
Sep 1, 2000·The American Journal of Medicine·J H GurwitzD W Bates
Apr 19, 2002·JAMA : the Journal of the American Medical Association·Peter M LaydeLeslie A Maas
Jul 23, 2002·JAMA : the Journal of the American Medical Association·Lucian L LeapeDavid W Bates
Dec 11, 2002·Journal of the American Geriatrics Society·Lawrence K GrayJoyce M Callahan
Dec 24, 2003·Journal of Critical Care·Peter PronovostPamela Lipsett
May 19, 2004·Annals of Internal Medicine·Jonathan R NebekerMatthew H Samore
Mar 2, 2005·Archives of Internal Medicine·Patricia L CornishEdward E Etchells
May 25, 2005·Archives of Internal Medicine·Jonathan R NebekerJohn F Hurdle
Oct 26, 2006·The American Journal of Geriatric Pharmacotherapy·Kenneth S BoockvarAlbert Siu
Feb 17, 2007·Medical Care·Denise M HynesLinda Kok
Oct 6, 2007·Joint Commission Journal on Quality and Patient Safety·Frank Federico
Jun 20, 2008·Journal of General Internal Medicine·Jennifer R PippinsJeffrey L Schnipper
Feb 11, 2009·Quality & Safety in Health Care·K S BoockvarT Fried
Oct 15, 2010·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Jeffrey L GreenwaldMark V Williams
May 11, 2011·Archives of Internal Medicine·Kenneth S BoockvarJessica Yeh
Aug 13, 2011·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Kenneth S BoockvarJonathan R Nebeker
Jun 27, 2012·Archives of Internal Medicine·Stephanie K MuellerJeffrey L Schnipper
Jul 4, 2012·Annals of Internal Medicine·Sunil KripalaniUNKNOWN PILL-CVD (Pharmacist Intervention for Low Literacy in Cardiovascular Disease) Study Group
Oct 24, 2012·Research in Social & Administrative Pharmacy : RSAP·Amy VogelsmeierCharlene Weir
Apr 16, 2014·Applied Clinical Informatics·J R VestR Kaushal
Jan 1, 2012·Medicare & Medicaid Research Review·Jennifer HumenskyDenise M Hynes
Dec 2, 2014·Annals of Internal Medicine·Robert S RudinPaul G Shekelle
Dec 19, 2015·JMIR Medical Informatics·William R HershMarian S McDonagh

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Citations

Aug 18, 2020·The Cochrane Database of Systematic Reviews·Natalie LeonKaren Daniels
Jan 28, 2020·JAMIA Open·Joshua R VestHye-Young Jung
May 3, 2018·Journal of the American Medical Informatics Association : JAMIA·Nir MenachemiJoshua R Vest
Mar 29, 2018·Journal of the American Medical Informatics Association : JAMIA·Aude MotulskyRobyn Tamblyn
Jul 28, 2019·Journal of the American Medical Informatics Association : JAMIA·Joshua R VestKosali Simon
Oct 18, 2020·Journal of the American Medical Informatics Association : JAMIA·Saurabh RahurkarBrian E Dixon
Nov 17, 2020·British Journal of Clinical Pharmacology·Rachel BryanSue Jordan
Nov 27, 2020·Therapeutic Advances in Drug Safety·Elizabeth ManiasAngela Wu
Oct 27, 2020·The Journal of Nursing Administration·Eun-Shim NahmLisa Rowen
Mar 1, 2021·International Journal of Medical Informatics·Ranganathan ChandrasekaranJohn Pendergrass
Jun 10, 2021·Applied Clinical Informatics·Masaharu NakayamaHiroaki Shimizu
Nov 26, 2021·The Cochrane Database of Systematic Reviews·Agustín CiapponiEzequiel Garcia-Elorrio

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