PMID: 2109945Apr 1, 1990Paper

Effect of hematocrit on behavioral thermoregulation of the toad Bufo marinus

The American Journal of Physiology
S C Wood

Abstract

This study tested the hypothesis that the oxygen capacity of blood, indexed by hematocrit, affects the body temperature (Tb) selected by toads (Bufo marinus) in a thermal gradient. Anesthetized toads (Brevital sodium; 40 mg/kg im) were fitted with a cloacal thermistor and femoral artery cannula. After recovery, they were placed in a thermal gradient ranging from approximately 10 to 40 degrees C. Tb was measured for 24 h. Then 1-2 ml blood were withdrawn and replaced with an equal volume of either 0.66% saline or packed red cells from donor toads. Selected Tb was measured for the next 24 h. The mean Tb selected by B. marinus (n = 33) was 24.9 degrees C. Cross-sectional analysis showed no correlation between selected Tb and hematocrit. However, each toad rendered anemic showed a reduction of selected Tb (mean = 22.9 degrees C). The degree of Tb reduction was correlated with the hematocrit reduction, (r = 0.86; P = 0.013). Blood doping did not have a significant effect on selected Tb. The reduction of Tb could be adaptive by reducing oxygen consumption.

Citations

Mar 11, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·R N RauschH L Wallace
Feb 5, 2002·Annual Review of Physiology·Alexandre A Steiner, Luiz G S Branco

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