Oct 1, 1990

Effect of hemodilution on systemic and capillary hematocrit

Infusionstherapie : offizielles Organ der Deutschen Arbeitsgemeinschaft für Künstliche Ernährung (DAKE) ; offizielles Organ der Österreichischen Arbeitsgemeinschaft für Klinische Ernähru (AKE) ; offizielles Organ der Deutschen Gesellschaft für Transfusion
F JungE Wenzel

Abstract

In a cross-over study including 10 clinically healthy male volunteers, the hematocrit in the macro- and microcirculation was investigated prior to and 1 h, 3 h, 6 h and 24 h after iso- or (3 months later) hypervolemic hemodilution using 500 ml hydroxyethyl starch. The dilution effect observed after isovolemic hemodilution is more pronounced than after hypervolemic hemodilution. While isovolaemic hemodilution with 500 ml medium molecular weight hydroxyethyl starch leads to a reduction in the systemic hematocrit by 8.5% by volume, the capillary hematocrit at the time of the most marked dilution (1 h after hemodilution) decreases by only 1.3 hematocrit points in the cutaneous capillaries. After hypervolemic hemodilution, the systemic hematocrit decreases significantly by maximally 5.4% by volume, while the capillary hematocrit does not change significantly.

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Mentioned in this Paper

Blood Flow Velocity
HAES-steril
Hemodilution
Blood Viscosity
Platelet Aggregation
Capillary Leak Syndrome
Rouleaux Formation, Erythrocyte
Hematocrit Procedure
Microcirculation
Erythrocyte Deformability

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