PMID: 9530599Apr 8, 1998Paper

Effect of heparin in irrigating solution on inflammation following small incision cataract surgery

Journal of Cataract and Refractive Surgery
T KohnenK W Jacobi

Abstract

To study the effect of heparin-sodium added to the irrigating solution on postoperative inflammation in patients having cataract surgery. Department of Ophthalmology, University of Giessen, Giessen, Germany. Seventy-two patients having phacoemulsification with posterior chamber intraocular lens (IOL) implantation were randomly assigned to receive regular irrigating solution or solution with heparin-sodium (final diluted concentration 10 IU/mL). In half the patients, poly(methyl methacrylate) (PMMA) IOLs were implanted and in half, foldable silicone IOLs. The patients were examined preoperatively, on days 1 and 3, and 1 year postoperatively. Postoperative inflammation was objectively evaluated by measurement of flare and cells using laser flare-cell photometry. The mean postoperative flare values were significantly lower in the groups with additional heparin-sodium at days 1 and 3 (P < . 01). Flare values were not significantly different 1 year postoperatively. Cell values for the heparin-treated groups were lower, but the difference did not reach statistical significance. Flare and cells values for the two IOL materials were not significantly different during the entire follow-up. Heparin-sodium added to the infusion solution d...Continue Reading

References

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Citations

Jun 23, 2007·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·T Kohnen, M Lüchtenberg
Dec 25, 2002·Journal of Cataract and Refractive Surgery·Huseyin Bayramlar, Ugur C Keskin
Apr 17, 2004·International Ophthalmology Clinics·Sean-Paul A AtreidesAdam C Reynolds
Jan 4, 2005·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Nhung X NguyenGottfried O H Naumann
Jul 12, 2014·Journal français d'ophtalmologie·C Chiquet, F Rouberol
Mar 14, 2000·Journal of Cataract and Refractive Surgery·V PetternelM Amon
Jul 11, 2002·Journal of Cataract and Refractive Surgery·Nhung Xuan NguyenUNKNOWN Erlangen Accommodative Intraocular Lens Study Group
Dec 13, 2003·Journal of Cataract and Refractive Surgery·Oliver FindlAndreas Kruger
Apr 13, 1999·Journal of Cataract and Refractive Surgery·O FindlJ Schauersberger
May 19, 2005·Journal of Cataract and Refractive Surgery·Charlotta ZetterströmMaria Kugelberg
Jan 5, 2002·Journal of Cataract and Refractive Surgery·Andreas KrugerJörg Schauersberger
Nov 24, 1999·Journal of Cataract and Refractive Surgery·J N NortonD D Koch
May 1, 2012·American Journal of Ophthalmology·Viraj A VasavadaAbhay R Vasavada
Oct 20, 2007·Acta Ophthalmologica Scandinavica·Charlotta Zetterström, Maria Kugelberg
Oct 12, 2004·Journal of Cataract and Refractive Surgery·Hüseyin BayramlarMehmet Borazan
Feb 24, 2006·American Journal of Ophthalmology·Shimon RumeltUri Rehany
Feb 24, 2006·American Journal of Ophthalmology·M Edward Wilson, Rupal H Trivedi
Jun 13, 2015·Advances in Pharmacological Sciences·Sarah MousaviMaryam Motamedi
Jan 13, 2017·Journal of Tissue Engineering and Regenerative Medicine·Alexander KöwitschThomas Groth

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