Effect of High-Intensity Interval Training on Body Composition, Cardiorespiratory Fitness, Blood Pressure, and Substrate Utilization During Exercise Among Prehypertensive and Hypertensive Patients With Excessive Adiposity

Frontiers in Physiology
Pedro Delgado-FloodyCristian Álvarez

Abstract

Regular exercise training is a recognized lifestyle strategy to lower resting blood pressure (BP), but little is known about substrate metabolism in population with high BP. Thus, the purpose of this study was to investigate the effects of 16-weeks of HIIT on body composition, BP, cardiorespiratory fitness by V . O2 max , and substrate utilization during exercise among prehypertensive and hypertensive patients with excessive adiposity. We also aimed to test the potential association between changes in cardiorespiratory fitness, substrate utilization during exercise and BP. Forty-two physically inactive overweight/obese participants participated in 16-weeks of HIIT intervention. The HIIT frequency was three times a week (work ratio 1:2:10, for interval cycling: rest period: repeated times; 80-100% of the maximum heart rate). Groups were distributed based on their baseline BP: HIIT-hypertensive (H-HTN: age 47.7 ± 12.0 years; body mass index [BMI] 30.3 ± 5.5 kg/m2; systolic [SBP]/diastolic BP [DBP] 151.6 ± 10/81.9 ± 4.2 mmHg), HIIT-pre-hypertensive (H-PreHTN: age 37.6 ± 12.0 years; BMI 31.9 ± 5.3 kg/m2; SBP/DBP 134.4 ± 3.2/74.9 ± 7.0 mmHg), and a normotensive control group (H-CG: age 40.7 ± 11.0 years; BMI 29.5 ± 4.2 kg/m2; S...Continue Reading

References

Nov 1, 1984·The American Journal of Medicine·R CadeD Hood-Lewis
Oct 1, 1995·The American Journal of Clinical Nutrition·K P KempenK R Westerterp
Dec 1, 1995·Journal of Applied Physiology·J A RomijnR R Wolfe
Mar 21, 1998·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·J ErikssonV Koivisto
Jun 15, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M A van Baak
Jun 16, 1999·Journal of Applied Physiology·A L FriedlanderG A Brooks
Mar 10, 2001·The American Journal of Clinical Nutrition·D P van Aggel-LeijssenM A van Baak
Jan 10, 2002·Medicine and Science in Sports and Exercise·Juul AchtenAsker E Jeukendrup
Jul 10, 2002·Obesity Research·Bret H GoodpasterDavid E Kelley
Dec 6, 2003·Hypertension·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Sep 18, 2004·The Journal of Physiology·Daniel J GreenRoger Taylor
Oct 25, 2006·Hypertension·François FeihlBernard I Levy
Feb 16, 2007·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Robert H Fagard, Véronique A Cornelissen
Mar 16, 2007·The New England Journal of Medicine·Stefan Neubauer
May 21, 2009·JAMA : the Journal of the American Medical Association·Satoru KodamaHirohito Sone
Apr 10, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Guilherme Veiga GuimarãesEdimar Alcides Bocchi
Apr 1, 2011·European Journal of Preventive Cardiology·Harald Edvard Molmen-HansenAsbjorn Stoylen
Feb 1, 2012·The Journal of Physiology·Martin J GibalaJohn A Hawley
Mar 10, 2012·Journal of Applied Physiology·Gurpreet K BirkDaniel J Green
Oct 2, 2015·Current Hypertension Reports·Linda S PescatelloBlair T Johnson
Nov 11, 2017·European Journal of Applied Physiology·Todd Anthony Astorino, Matthew M Schubert
Dec 1, 2017·Revista médica de Chile·Fanny PetermannCarlos Celis-Morales
Feb 10, 2018·Revista médica de Chile·María Angélica OleaErik Díaz
Mar 3, 2018·International Journal of Molecular Sciences·Alessia RussoGiuseppe Matullo
Aug 28, 2018·Revista médica de Chile·Johnattan Cano-MontoyaCristian Álvarez
Feb 6, 2019·Lipids in Health and Disease·Robinson Ramírez-VélezRonald G Garcia
Aug 1, 2019·Clinical and Experimental Hypertension : CHE·Mohammad SoltaniSajad Ahmadizad
Aug 7, 2019·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Pedro Delgado-FloodyMikel Izquierdo

❮ Previous
Next ❯

Methods Mentioned

BETA
Pharmacotherapy

Software Mentioned

GraphPad Prism
SPSS
GraphPad
Power

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.