Effect of High-Intensity Interval Training Versus Moderate-Intensity Aerobic Continuous Training on Galectin-3 Gene Expression in Postmenopausal Women: A Randomized Controlled Trial

Journal of Aging and Physical Activity
Diana KeyhaniAna Maria Botelho Teixeira

Abstract

Galectin-3 is a pro-inflammatory biomarker associated with the pathogenesis of heart failure (HF). Physical-activity reduces the risk of heart-failure by modification of inflammation and fibrosis. The purpose of this study was to compare the effects of 8 weeks of high-intensity interval training (HIIT) versus moderate-intensity aerobic continuous training on a predictive factor of HF in postmenopausal women. Thirty sedentary postmenopausal women were randomly assigned to three groups. The first group performed the HIIT program at 60%-90%, and the second group performed an exercise program at 50%-65% of HR reserve. The control group maintained their normal daily regular physical activity level. The gene expressions of galectin-3 and lipid profiles were measured at the baseline and the end of Week 8. The HIIT and moderate-intensity aerobic continuous training attenuated the gene expression of galectin-3, serum low-density lipoprotein, cholesterol, and triglyceride concentrations and enhanced high-density lipoprotein concentrations. These changes were considerably higher in the HIIT group. Our results show that HIIT is superior to moderate-intensity aerobic continuous training in improving the decrease in HF risk in postmenopausal...Continue Reading

References

Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
Mar 17, 2007·Climacteric : the Journal of the International Menopause Society·G M C RosanoM Volterrani
Jun 25, 2009·Exercise and Sport Sciences Reviews·Ulrik WisløffOle J Kemi
Aug 4, 2009·European Journal of Heart Failure·Rudolf A de BoerDirk J van Veldhuisen
Oct 3, 2009·Metabolism: Clinical and Experimental·Fabien PillardLaurent Brondel
Apr 29, 2010·Current Heart Failure Reports·Rudolf A de BoerDirk J van Veldhuisen
Sep 25, 2010·Scandinavian Journal of Medicine & Science in Sports·P B Laursen
Apr 1, 2011·European Journal of Preventive Cardiology·Harald Edvard Molmen-HansenAsbjorn Stoylen
Oct 27, 2011·Journal of Internal Medicine·R A de BoerP van der Harst
Dec 14, 2011·European Heart Journal·André La GercheDavid L Prior
Feb 1, 2012·The Journal of Physiology·Martin J GibalaJohn A Hawley
Feb 23, 2012·Circulation·Gene Kwan, Gary J Balady
Dec 15, 2012·Circulation·Alan S GoUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
May 8, 2013·European Journal of Heart Failure·Rudolf A de BoerBurkert Pieske
Sep 18, 2013·Diabetes, Obesity & Metabolism·M A NimmoJ A King
Jan 7, 2014·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Behzad Hajizadeh MalekiDiana Vaamonde
Jan 28, 2014·European Journal of Heart Failure·Luc DjousséJ Michael Gaziano
Jul 1, 2014·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Behzad Hajizadeh Maleki, Bakhtyar Tartibian
Apr 25, 2015·European Journal of Ophthalmology·Selim DereciBumin Dundar
Apr 16, 2016·Circulation Research·Mariana GarciaJoAnn E Manson
Nov 3, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Germán E GonzálezOscar A Carretero
Aug 20, 2016·Journal of the Neurological Sciences·Xin-Jiang YanWei-Min Dai
Oct 22, 2016·European Journal of Heart Failure·Wouter C MeijersRudolf A de Boer
Dec 7, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·Behzad Hajizadeh MalekiMohammad Chehrazi
Jun 8, 2017·BioMed Research International·Małgorzata ŻychowskaStanisław Sawczyn
Nov 1, 2017·Menopause : the Journal of the North American Menopause Society·Joan A GrossmanJessica L Bachman
Nov 21, 2017·Heart Failure Clinics·Carolin GehlkenRudolf A de Boer
May 15, 2018·Translational Research : the Journal of Laboratory and Clinical Medicine·Hao WangLeanne Groban

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.