Effect of Hybrid stage 1 procedure on ventricular function in infants with hypoplastic left heart syndrome

Cardiology in the Young
Daisuke KobayashiSanjeev Aggarwal

Abstract

The effect of Hybrid stage 1 palliation for hypoplastic left heart syndrome on right ventricular function is unknown. We sought to compare right ventricular function in normal neonates and those with hypoplastic left heart syndrome before Hybrid palliation and to assess the effect of Hybrid palliation on right ventricular function, using the right ventricular myocardial performance index and the ratio of systolic and diastolic durations. We carried out a retrospective review of echocardiographic data on 23 infants with hypoplastic left heart syndrome who underwent Hybrid palliation and 35 normal controls. Data were acquired before Hybrid and after Hybrid palliation - post 1, 0-4 days; post 2, 1 week; post 3, 2-3 weeks; post 4, 1-1.5 months following Hybrid palliation. Myocardial performance index and ratio of systolic and diastolic durations were higher in the pre-Hybrid hypoplastic left heart syndrome group (n=23) - 0.47±0.16 versus 0.25±0.07, p<0.001; 1.59±0.44 versus 1.09±0.14, p<0.0001 - compared with controls (n=35). There was no significant change in the myocardial performance index at any of the post-Hybrid time points. Ratio of systolic and diastolic durations increased significantly 2 weeks after Hybrid - post 3: 2.08±...Continue Reading

References

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Nov 1, 1958·Pediatric Clinics of North America·J A NOONAN, A S NADAS
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Oct 14, 2011·Circulation·Tain-Yen HsiaUNKNOWN Modeling of Congenital Hearts Alliance (MOCHA) Investigators

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Citations

Apr 18, 2019·Cardiology in the Young·Pilar Anton-MartinBrigham C Willis

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