Abstract
In an attempt to investigate the effect of Hymenolepis nana infection on immunological responses to sRBC in ICR strain of mice, cellular and humoral immune responses were chronologically monitored after sensitization with sRBC. Mice weighing about 20 g were allocated into artificial and natural infection groups. The shell-free eggs of H. nana were inoculated into mice on the day 0 (initial) and day 10 in the former group, and praziquantel (25 mg/kg/day) was administered for 3 days to the one half of the mice at the 15th day after the first inoculation and to all of the mice in natural infection group. In artificial infection group, the delayed-type hypersensitivity (DTH) to sRBC was considerably decreased on the day 10 after the first inoculation, and then elevated gradually to normal. Eosinophils in the peripheral blood increased slightly. The hemagglutinin (HA) and hemolysin (HE) titers during the early stage were shown to be more or less higher than those of control. Thereafter, the titers were returned to normal, followed by a transient decrease on the day 15 post-infection. The sRBC rosette and antibody-treated rosette-forming capacities on the day 15 post-infection were temporarily lowered but became higher thereafter. Th...Continue Reading
References
Mar 1, 1977·The Journal of Experimental Medicine·D I GroveK S Warren
Jan 1, 1977·International Archives of Allergy and Applied Immunology·D D IsaakN D Reed
Apr 1, 1971·Laboratory Animals·H J Griffiths
Jan 1, 1972·Cellular Immunology·J F Bach, M Dardenne
Aug 1, 1981·Journal of Clinical Pathology·S StrobelA Ferguson
Jun 1, 1984·Experimental Parasitology·D Hoole, J B Mitchell
Jul 1, 1981·The American Journal of Tropical Medicine and Hygiene·F KierszenbaumG J Gleich
Aug 1, 1982·Experimental Parasitology·A Ito
Aug 1, 1981·International Journal for Parasitology·T FurukawaT Miyazato
Apr 1, 1981·Journal of Comparative Pathology·R W Cook, J F Williams
Jan 15, 1980·Experientia·R K GuptaG N Johri
Apr 1, 1980·Experimental Parasitology·A Ito
Aug 1, 1961·The Journal of Infectious Diseases·D HEYNEMAN
Jan 1, 1962·The American Journal of Tropical Medicine and Hygiene·D HEYNEMAN
Citations
Sep 1, 1991·Kisaengch'unghak chapchi. The Korean journal of parasitology·J K RheeY S Seu
Apr 8, 1998·The Korean Journal of Parasitology·J K RheeB K Park
Feb 3, 1998·The Korean Journal of Parasitology·J K RheeH C Kim