Effect of including damage at the tissue level in the nonlinear homogenisation of trabecular bone

Biomechanics and Modeling in Mechanobiology
Francesc Levrero-FlorencioPankaj Pankaj

Abstract

Being able to predict bone fracture or implant stability needs a proper constitutive model of trabecular bone at the macroscale in multiaxial, non-monotonic loading modes. Its macroscopic damage behaviour has been investigated experimentally in the past, mostly with the restriction of uniaxial cyclic loading experiments for different samples, which does not allow for the investigation of several load cases in the same sample as damage in one direction may affect the behaviour in other directions. Homogenised finite element models of whole bones have the potential to assess complicated scenarios and thus improve clinical predictions. The aim of this study is to use a homogenisation-based multiscale procedure to upscale the damage behaviour of bone from an assumed solid phase constitutive law and investigate its multiaxial behaviour for the first time. Twelve cubic specimens were each submitted to nine proportional strain histories by using a parallel code developed in-house. Evolution of post-elastic properties for trabecular bone was assessed for a small range of macroscopic plastic strains in these nine load cases. Damage evolution was found to be non-isotropic, and both damage and hardening were found to depend on the loading...Continue Reading

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Citations

Apr 22, 2017·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Francesc Levrero-FlorencioPankaj Pankaj
Jun 6, 2018·Frontiers in Physiology·Francesc Levrero-Florencio, Pankaj Pankaj
Apr 26, 2021·International Journal for Numerical Methods in Biomedical Engineering·Xuan Nam DoJean-François Ganghoffer

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Software Mentioned

ParaFEM
ARCHER
BoneJ

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