Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trial

Circulation
Claudia WaltherGerhard Schuler

Abstract

The aim of this prospective, randomized study was to examine whether additional school exercise lessons would result in improved peak oxygen uptake (primary end point) and body mass index-standard deviation score, motor and coordinative abilities, circulating progenitor cells, and high-density lipoprotein cholesterol (major secondary end points). Seven sixth-grade classes (182 children, aged 11.1+/-0.7 years) were randomized to an intervention group (4 classes with 109 students) with daily school exercise lessons for 1 year and a control group (3 classes with 73 students) with regular school sports twice weekly. The significant effects of intervention estimated from ANCOVA adjusted for intraclass correlation were the following: increase of peak o(2) (3.7 mL/kg per minute; 95% confidence interval, 0.3 to 7.2) and increase of circulating progenitor cells evaluated by flow cytometry (97 cells per 1 x 10(6) leukocytes; 95% confidence interval, 13 to 181). No significant difference was seen for body mass index-standard deviation score (-0.08; 95% confidence interval, -0.28 to 0.13); however, there was a trend to reduction of the prevalence of overweight and obese children in the intervention group (from 12.8% to 7.3%). No treatment ...Continue Reading

References

Jan 1, 1978·The American Journal of Cardiology·G R CummingL Hastman
Aug 6, 1998·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·U Ravens-Sieberer, M Bullinger
Jul 7, 2000·The New England Journal of Medicine·M J StampferW C Willett
Jul 18, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K S Steinbeck
Sep 6, 2002·The New England Journal of Medicine·Sue Y S KimmKiang Liu
Apr 25, 2003·The Journal of Pediatrics·Rae-Ellen W KaveyUNKNOWN American Heart Association
May 23, 2003·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·W H M SarisH Wyatt
Feb 28, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Volker AdamsRainer Hambrecht
Aug 24, 2004·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Stefanie Dimmeler, Andreas M Zeiher
Apr 20, 2005·Circulation·Stephen R DanielsChristine L Williams
Sep 9, 2005·The New England Journal of Medicine·Nikos WernerGeorg Nickenig
Jan 27, 2006·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·C M DoakJ C Seidell
Aug 17, 2006·European Heart Journal·Gian Paolo FadiniAngelo Avogaro
Dec 13, 2006·Journal of Applied Physiology·Greta L HoetzerChristopher A DeSouza
Dec 16, 2006·Endothelium : Journal of Endothelial Cell Research·Brendan DoyleNoel M Caplice
Aug 5, 2008·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Claudia WaltherGerhard Schuler
Dec 17, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·O J MacEneaneyC A DeSouza
Jan 1, 1998·American Journal of Human Biology : the Official Journal of the Human Biology Council·Katrin Kromeyer-Hauschild, U Jaeger

❮ Previous
Next ❯

Citations

Feb 4, 2011·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·C MeyerT Rassaf
Nov 3, 2012·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Konstantinos A VolaklisMartin Halle
Jun 22, 2010·Current Gastroenterology Reports·Miriam B Vos, Jean Welsh
Nov 26, 2010·Antioxidants & Redox Signaling·Sven Moebius-WinklerVolker Adams
Oct 30, 2010·Physical Therapy·Fabrisia AmbrosioAlan J Russell
Dec 29, 2012·World Journal of Cardiology·Matina KoutroumpiSerafim Nanas
Jan 23, 2013·Current Opinion in Cardiology·Jose A CanasPrabhakaran Babu Balagopal
Aug 30, 2014·International Journal of Environmental Research and Public Health·Melinda J IckesManoj Sharma
Sep 2, 2014·Preventive Medicine·Claudia Ciceri CesaLucia Campos Pellanda
Dec 18, 2013·Metabolism: Clinical and Experimental·Andreas OberbachHolger Till
Sep 24, 2013·Journal of the Academy of Nutrition and Dietetics·Deanna M HoelscherUNKNOWN Academy Positions Committee
May 22, 2013·Oxidative Medicine and Cellular Longevity·Luc BruyndonckxViviane M Conraads
May 21, 2011·Revista española de cardiología·Daniel N ArdoyFrancisco B Ortega
Jul 22, 2015·Medicine and Science in Sports and Exercise·Sagano OnoyamaChung-Cheng Hsieh
Dec 2, 2015·Scandinavian Journal of Medicine & Science in Sports·C T RexenL B Andersen
Jun 8, 2012·The Journal of Clinical Hypertension·Julie R Ingelfinger, Anne-Monique Nuyt
Dec 22, 2009·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Attila TárnokJozsef Bocsi
Jul 23, 2014·Scandinavian Journal of Medicine & Science in Sports·C T RexenL B Andersen
Sep 10, 2015·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Melitta A McNarryJames Faulkner
Apr 22, 2015·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Y WangJ Segal
Sep 30, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·L CaiY Wang
Apr 5, 2012·Experimental Diabetes Research·Alessandra PetrelliPaolo Fiorina
Jul 20, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M OosterhoffI Ferreira
Mar 22, 2012·Obesity Facts·Susanne BrandstetterMartin Wabitsch
Dec 15, 2012·The Journal of School Nursing : the Official Publication of the National Association of School Nurses·Emily H MorganJennifer M Sacheck
Feb 13, 2016·European Journal of Preventive Cardiology·Ulrike M MüllerGerhard Schuler
Mar 21, 2018·Journal of Sports Sciences·Dominique Silva SilveiraClarice Maria de Lucena Martins
Mar 2, 2013·The Cochrane Database of Systematic Reviews·Maureen DobbinsRebecca L LaRocca
Feb 14, 2018·Journal of the American Heart Association·Ephraim Bernhard WinzerAxel Linke
Oct 28, 2017·British Journal of Sports Medicine·Diana P Pozuelo-CarrascosaVicente Martinez-Vizcaino
Jun 22, 2016·Circulation·Scott KinlayJane A Leopold
Nov 19, 2009·Circulation·Reginald L Washington
Dec 21, 2011·Circulation·Joseph A Vita
Apr 4, 2015·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Gioia MuraMauro Giovanni Carta
Nov 12, 2015·Pediatric Cardiology·Eric J KortStefan Jovinge

❮ Previous
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