PMID: 847231Feb 1, 1977Paper

Effect of indomethacin on atropine-resistant transmission in rabbit and monkey urinary bladder: evidence for involvement of prostaglandins in transmission

Prostaglandins
A Johns, D M Paton

Abstract

The effects of 2.9 x 10(-5)M atropine and 2.8 x 10(-6)M indomethacin on responses of rabbit and monkey detrusor muscle to transmural stimulation were investigated. Response to transmural stimulation were partially inhibited by atropine. Indomethacin caused further inhibition in the presence of atropine, but did not alter responses to acetylcholine. Prostaglandins E2 and F2alpha contracted rabbit and monkey detrusor. It is suggested that prostaglandins are liberated during stimulation of excitatory nerves to the rabbit and monkey detrusor, and contribute to the resultant contractile response.

References

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Citations

Jan 1, 1989·Pflügers Archiv : European journal of physiology·K E Creed, S M Callahan
Apr 6, 1984·European Journal of Pharmacology·P A LonghurstD P Westfall
Apr 7, 1992·European Journal of Pharmacology·P Sneddon, A McLees
Feb 9, 1981·Life Sciences·J W Downie, S Rouffignac
Jan 1, 1982·Progress in Neurobiology·K E Andersson, C Sjögren
Nov 23, 2013·Purinergic Signalling·Geoffrey Burnstock
Aug 1, 1980·British Journal of Pharmacology·M Alkondon, D K Ganguly
Jan 26, 2010·The Journal of Urology·Mohammad Sajjad Rahnama'iJames I Gillespie
Feb 1, 1981·British Journal of Urology·I M KhalafM M Elhilali
Jan 1, 1983·Scandinavian Journal of Urology and Nephrology·A Nergårdh, A C Kinn
Jan 1, 1981·Scandinavian Journal of Urology and Nephrology·A Nergårdh
Dec 19, 2013·Nephro-urology Monthly·Mohammad Sajjad Rahnama'iPhilip E Van Kerrebroeck
Jun 15, 2011·Physiology·Ye Chun RuanHsiao Chang Chan
Jan 1, 1980·Acta Pharmacologica Et Toxicologica·S HustedJ R Ostergaard
Oct 11, 2017·Annual Review of Pharmacology and Toxicology·Sang Don KohKenton M Sanders
Mar 25, 2021·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Nagat FraraMichael R Ruggieri

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