PMID: 7087669Apr 19, 1982Paper

Effect of infusing the branched-chain amino acids on concentrations of amino acids in plasma and brain and on brain catecholamines after total hepatectomy in the rat

Life Sciences
J H JamesJ E Fischer


In totally hepatectomized rats supported by infusion of glucose, the concentrations of many amino acids in plasma and brain rose progressively over time, while the brain levels of norepinephrine decreased. Infusion of a solution containing glucose, leucine, isoleucine, and valine after hepatectomy greatly reduced the accumulation of other essential amino acids in plasma and brain. However, the decrease in brain norepinephrine content was not significantly affected by this infusion, suggesting that high brain concentrations of monoamine precursor amino acids are not the primary cause of norepinephrine depletion after hepatectomy.


Mar 1, 1978·Life Sciences·G M Tyce, C A Owen


Sep 1, 1992·Journal of Neurochemistry·Cornelis H C DejongPeter B Soeters
May 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·L Marsano, C J McClain
May 22, 2007·The Journal of Nutrition·Cornelis H C DejongSteven W M Olde Damink

Related Concepts

Amino Acids, Branched-Chain
Brain Chemistry
Anhydrous Dextrose
Parenteral Infusion
Norepinephrine, (+, -)-Isomer
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