PMID: 11309185Apr 20, 2001Paper

Effect of inner cannula removal on the work of breathing imposed by tracheostomy tubes: a bench study

Respiratory Care
T CowanP Kulkarni

Abstract

Tracheotomy has been used to assist in weaning patients from mechanical ventilation. Some patients fail to be weaned from the ventilator despite tracheostomy. We hypothesized that removing the inner cannula from the tracheostomy tube would decrease the tube's imposed work of breathing (WOB(IMP)). The hypothesis was tested using a lung model, by measuring the change in WOB(IMP) when the inner cannula was removed. A mechanical lung model was developed using a test lung to simulate a spontaneously breathing patient. WOB(IMP) was measured with a commercially available lung mechanics monitor. Shiley size 6, 8, and 10 nonfenestrated tracheostomy tubes were tested with the inner cannula in and out. Breathing conditions were simulated using tidal volumes (V(T)) of 300 and 500 mL matched with breathing frequencies of 12, 24, and 32 breaths per minute, by using a ventilator to simulate spontaneous breathing through one side of the test lung. Under all the tested breathing conditions, WOB(IMP) for each of the 3 tracheostomy tubes was significantly reduced (p < 0.05) when the inner cannula was removed. Also, as simulated spontaneous inspiratory flow demand increased (ie, as V(T) and/or frequency were increased), WOB(IMP) also increased, an...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.