PMID: 488458Sep 1, 1979Paper

Effect of inspiratory resistance loading on temporal parameters of respiration in anesthetized cats

Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
N Z Kliueva

Abstract

In anesthetized cats, an increase in inspiratory resistance in conditions of growing hypercapnia entailed elongation of inspiration and of the whole respiratory cycle, as well as decrease of the volume threshold for cessation of inspiration. The latter occurred after bilateral vagotomy too, whereas no significant changes of the temporal parameters followed the increase in the resistance. The temporal rearrangements of the respiratory cycle seem to be due to the vagal effects, while the extravagal influences, probably the reflexes from the stretch receptors of intercostal muscles, are responsible for changes of the volume component in the relations characterizing the mechanism of cessation of inspiration.

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