Effect of interlaminar epidural steroid injection in acute and subacute pain due to lumbar disk herniation: a randomized comparison of 2 different protocols.

The Open Orthopaedics Journal
I D GelalisG Papadopoulos

Abstract

In order to assess the efficacy of epidural steroid injections (ESI) in acute and subacute pain due to lumbar spine disk herniation, we conducted a randomized trial, comparing 2 different protocols. Fourty patients with radicular pain due to L4-L5 and L5-S1 disc herniation were assigned to receive either 3 consecutive ESI every 24 hours through a spinal catheter (group A) or 3 consecutive ESI every 10 days with an epidural needle (group B). All patients had improved Oswestry Disabilty Index (ODI) and the Visual Analog Scale (VAS) for pain scores at 1 month of follow-up compared to baseline, while no significant differences were observed between the 2 groups. The scores for group B were statistically significant lower at 2 months of follow-up compared to those of group A. The improvement in the scores of group B was continuous since the mean scores at 2 months of follow up were lower compared to the respective scores at 1 month. Protocol B (3 consecutive ESI every 10 days) was found more effective in the treatment of subacute pain compared to Protocol A (3 consecutive ESI every 24 hours) with statistically significant differences in the ODI and VAS scores at 2 months of follow-up.

References

Jan 1, 1977·Acta Orthopaedica Scandinavica·W SnoekB Jørgensen
Jun 5, 1997·The New England Journal of Medicine·S CaretteC Blanchette
Feb 24, 2001·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G ByrödK Olmarker
May 10, 2002·Annals of the New York Academy of Sciences·R MelzackA L Vaccarino
Mar 19, 2005·The Journal of Bone and Joint Surgery. British Volume·J Wilson-MacDonaldC Glynn
Jul 28, 2005·Joint, Bone, Spine : Revue Du Rhumatisme·Denis MullemanPhilippe Goupille
Dec 17, 2005·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Warren A Katz, Russell Rothenberg
Feb 17, 2006·Acta Anaesthesiologica Scandinavica·J CassutoM Bonderovic
Aug 4, 2006·The Journal of the American Academy of Orthopaedic Surgeons·Francis H ShenGunnar B J Andersson
Jan 11, 2007·Prostate Cancer and Prostatic Diseases·P A S JohnstoneV Master
Mar 7, 2007·Neurology·Carmel ArmonUNKNOWN Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
Apr 12, 2007·The Journal of the American Academy of Orthopaedic Surgeons·Irene A YoungAndrew J Cole
May 28, 2008·Archives of Physical Medicine and Rehabilitation·Janna FriedlyCharles Maynard

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Citations

Dec 31, 2015·Drugs in R&D·Ippokratis PountosPeter V Giannoudis
Feb 12, 2014·Clinical Orthopaedics and Related Research·Laxmaiah ManchikantiJoshua A Hirsch
Aug 17, 2021·Turkish Journal of Physical Medicine and Rehabilitation·Merve Akdeniz LeblebicierTülay Erçalık

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