Effect of interleukin-1 on the augmentation of human immunodeficiency virus gene expression.

Biochemical and Biophysical Research Communications
N KobayashiN Yamamoto

Abstract

Among the cytokines tested here (IL-2, IL-3, IL-4, IL-5, IL-6, granulocyte colony stimulating factor (G-CSF), granulocyte/macrophage colony stimulating factor (GM-CSF), interferon-alpha (IFN-alpha), interferon-beta (IFN-beta) and interferon-gamma (IFN-gamma] only interleukin 1(IL-1) augmented HIV-long terminal repeat(LTR) directed chloramphenicol acetyl transferase(CAT) activity in protein kinase C(PKC)-independent manner. However, a stimulation by IL-1 was not as efficient as that due to tumor necrosis factor and the HIV production was not significant. IL-1 was not cytotoxic to MOLT-4/HIV cells.

References

Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·L OsbornG J Nabel
Mar 16, 1989·Nature·P Bacchetti, A R Moss

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Citations

Jan 1, 1995·International Journal of Clinical & Laboratory Research·N Yamamoto
Mar 5, 1998·Clinical and Experimental Immunology·C J De HaasJ Verhoef
Dec 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·N KobayashiS Yonehara
Jul 7, 1998·The Journal of Experimental Medicine·T W ChunA S Fauci
Jan 22, 2004·Viral Immunology·Aldar S BourinbaiarVichai Jirathitikal
May 10, 2001·Clinical Obstetrics and Gynecology·L al-Harthi, A Landay
Apr 13, 2010·Retrovirology·Georges Herbein, Audrey Varin
Jun 22, 2000·Medical Hypotheses·P A Corley
Aug 16, 2018·The Journal of Gene Medicine·Swati Ahir-BistJayanti Mania-Pramanik
Feb 1, 1991·Clinical and Experimental Immunology·D P DooleyD J Looney

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