Effect of intrafragmentary bupivacaine (haematoma block) on analgesic requirements in dogs undergoing fracture repair

Veterinary Anaesthesia and Analgesia
Irene DimopoulouMichael Patsikas

Abstract

To test the efficacy of intraoperative intrafragmentary administration of bupivacaine (haematoma block) in controlling postoperative pain in dogs undergoing osteosynthesis of long-bone isolated diaphyseal fractures. Randomized, 'blinded', placebo-controlled, prospective study. A total of 23 client-owned dogs with isolated long-bone fractures. Dogs were allocated randomly to two groups: bupivacaine group (B) or placebo group (P). Group B dogs (n = 11) were administered an intraoperative intrafragmentary injection of 0.5% bupivacaine (1.1 mg kg-1) just before fracture fixation, whereas group P dogs (n = 12) were administered normal saline. Postoperative pain evaluations using the University of Melbourne Pain Scale (UMPS) and algometer were performed upon arrival to the recovery room and 1, 2, 4, 6, 8, 20 and 32 hours later. Algometer measurements were performed on: the incision site, a healthy region near the fracture line and the contralateral healthy limb. When the pain score exceeded 14 points in the UMPS, rescue analgesia was administered. The time-standardised area under the curve (AUCst) was used to compare UMPS scores and mechanical pain thresholds between the two groups. None of the group B dogs required rescue analgesia,...Continue Reading

References

Jan 27, 1990·BMJ : British Medical Journal·J N MatthewsP Royston
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Feb 24, 2004·The American Journal of Sports Medicine·Damon H PettyJames R Andrews
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Feb 10, 2011·Veterinary Anaesthesia and Analgesia·Jinuk ParkGonhyung Kim
Aug 21, 2013·Acta Veterinaria Scandinavica·Bruno W MintoClaudia V S Brandão

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