PMID: 9546267Apr 18, 1998Paper

Effect of intratympanic steroid application on the development of experimental cholesteatoma

The Laryngoscope
L SennarogluE Turan

Abstract

By introducing certain irritants into the middle ear it is possible to produce cholesteatoma. Propylene glycol, the main agent used for this purpose, produces a long-standing inflammation that causes hyperplasia and migration of the epithelium through an intact tympanic membrane. In the present investigation topical prednisolone was used in order to inhibit the production of cholesteatoma. The results indicate that there is a marked decrease in inflammation and hence experimental cholesteatoma production when prednisolone is administered into the middle ear.

References

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Citations

Jul 4, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Patrick J AntonelliPhilip J Barr
Dec 10, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jason G WilmothPatrick J Antonelli
Feb 15, 2013·The Journal of Laryngology and Otology·A A MeloA J C Campos
Aug 27, 2005·Neurosurgical Focus·Eve C TsaiJames T Rutka
Oct 2, 2003·The Laryngoscope·Patrick J AntonelliPhilip J Barr
Jan 23, 2021·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Ramazan OcalNecmi Arslan
Nov 5, 2021·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Numan KoktenMahmut Tayyar Kalcioglu

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