PMID: 1214289Dec 4, 1975Paper

Effect of ionic polarizability on electrodiffusion in lipid bilayer membranes

The Journal of Membrane Biology
R W Bradshaw, C R Robertson

Abstract

Ion-carrier complexes and organic ions of similar size and shape have mobilities in lipid bilayer membranes which span several orders of magnitude. In this communication, an examination is made of the hypothesis that the basis for this unusually wide range of ionic mobilities is the potential energy barrier arising from image forces which selectively act on ions according to their polarizability. Using Poisson's equation to evaluate the electrostatic interaction between an ion and its surroundings, the potential energy barrier to ion transport due to image effects is computed, with the result that the potential energy barrier height depends strongly on ionic polarizability. Theoretical membrane potential energy profile calculations are used in conjunction with Nernst-Planck electrodiffusion equation to analyze the available mobility data for several ion-carrier complexes and lipid-soluble ions in lipid bilayer membranes. The variation among the mobilities of different ions is shown to be in agreement with theoretical predictions based on ionic polarizability and size. Furthermore, the important influence exerted by image forces on ion transport in lipid bilayer membranes compared to the frictional effect of membrane viscosity i...Continue Reading

References

Feb 28, 1975·Biochimica Et Biophysica Acta·R Benz, G Stark
Sep 10, 1974·Biochemistry·J M Vanderkooi, J B Callis
May 1, 1972·Quarterly Reviews of Biophysics·D A Haydon, S B Hladky
Sep 27, 1973·Biochimica Et Biophysica Acta·R H Tredgold
Dec 22, 1973·Biochimica Et Biophysica Acta·F GambaleM Robello
Feb 26, 1974·Biochimica Et Biophysica Acta·H J Galla, E Sackmann
Apr 1, 1974·Chemistry and Physics of Lipids·K Jacobson, D Wobschall
May 30, 1974·Biochimica Et Biophysica Acta·S B Hladky
Jun 20, 1972·Biochimica Et Biophysica Acta·G StarkK Janko
Jan 1, 1969·Biochimica Et Biophysica Acta·O H Le Blanc
Sep 1, 1971·The Journal of Membrane Biology·B KettererP Läuger
Sep 1, 1971·The Journal of Membrane Biology·R FettiplaceD A Haydon

❮ Previous
Next ❯

Citations

Dec 15, 1977·The Journal of Membrane Biology·F S CohenS McLaughlin
Feb 1, 1979·Biophysical Journal·S K Rangarajan, R de Levie
Mar 20, 2002·Accounts of Chemical Research·Jay T Groves, Steven G Boxer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.