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Effect of ionic strength and ionic composition of assay buffers on the interaction of thyroxine with plasma proteins

The Journal of Endocrinology

Sep 1, 1975

R L SutherlandM W Simpson-Morgan

PMID: 447

Abstract

When plasma proteins are diluted with buffer the ionic strength and ionic composition of that buffer affects the interactions between thyroxine (T4) and its plasma protein-binding sites. Increases in phosphate, chloride or barbiturate ion concentration from 50 to 200 mmol/l caused a sig...read more

Mentioned in this Paper

Hydrogen-Ion Concentration
Chloride Measurement
Thyroxine Measurement
Assay
Barbituric acid salt
Ampholytes
Phosphate ion
Orthophosphate
Inorganic phosphate
Plasma Proteins
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Effect of ionic strength and ionic composition of assay buffers on the interaction of thyroxine with plasma proteins

The Journal of Endocrinology

Sep 1, 1975

R L SutherlandM W Simpson-Morgan

PMID: 447

DOI:

Abstract

When plasma proteins are diluted with buffer the ionic strength and ionic composition of that buffer affects the interactions between thyroxine (T4) and its plasma protein-binding sites. Increases in phosphate, chloride or barbiturate ion concentration from 50 to 200 mmol/l caused a sig...read more

Mentioned in this Paper

Hydrogen-Ion Concentration
Chloride Measurement
Thyroxine Measurement
Assay
Barbituric acid salt
Ampholytes
Phosphate ion
Orthophosphate
Inorganic phosphate
Plasma Proteins

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