Effect of isometamidium on infections by Trypanosoma vivax and T. evansi in experimentally-infected animals

Veterinary Parasitology
M ToroA Ruíz

Abstract

Assays dealing with the therapeutic and prophylactic activity of isometamidium on experimental infections by Trypanosoma vivax and T. evansi were carried out. The drug was found to be highly effective against T. vivax infection in sheep and cattle in which periods of protection ranging from 118 to 195 days were achieved. No complete effects against infection by T. evansi were observed. The drug was well tolerated in sheep and cattle while side-effects were noted in treated mares. It was concluded that isometamidium could be used to prevent damage and economical losses caused by T. vivax in Venezuela.

References

Sep 1, 1969·Canadian Journal of Zoology·P T Woo
Jun 28, 1969·Nature·A W Edwards

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Citations

Jan 1, 1988·Veterinary Research Communications·B H Ali
Dec 1, 2009·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·Upendra KumarJ D Ghosh
Feb 9, 1999·Veterinary Parasitology·I E El RayahK H El Malik
Oct 11, 2016·Parasitology·Federica GiordaniMichael P Barrett
Sep 1, 1988·Journal of Veterinary Pharmacology and Therapeutics·L D Kinabo, J A Bogan
Jun 1, 1985·Journal of Veterinary Pharmacology and Therapeutics·B H AliK H Malik
Sep 13, 2018·PLoS Neglected Tropical Diseases·Gebrekrustos MekonnenHadush Birhanu
Jun 13, 2019·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Jessica Teles EcheverriaFernando de Almeida Borges
Apr 29, 2021·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Kayo José Garcia de Almeida Castilho NetoFabiano Antonio Cadioli

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