Effect of L-carnitine administration on the seminal characteristics of oligoasthenospermic stallions

Theriogenology
G StradaioliM Monaci

Abstract

The effect of orally administered l-carnitine on the quality of semen obtained from stallions with different semen qualities was investigated. Four stallions with proven fertility (high motility group, HM) and with normal seminal characteristics (>50% progressive motility and > 80 x 10(6) spermatozoa/ml), and four questionable breeders (low motility group, LM) with <50% of sperm progressive motility and < 80 x 10(6) spermatozoa/ml, received p.o. 20 g of l-carnitine for 60 days. Blood and semen samples were collected before treatment (T0) and after 30 (T1) and 60 days (T2). Semen evaluation were performed on five consecutive daily ejaculates (n = 120 ejaculates) and conventional semen analysis was carried out on each ejaculate, both at collection and after refrigeration for 24, 48, and 72 h. Furthermore l-carnitine, acetylcarnitine, pyruvate, and lactate concentrations, and carnitine acetyltransferase activity (CAT) were determined both in raw semen and seminal plasma. There were an increase in progressive motile spermatozoa only in the LM group (26.8 +/- 12.9, 39.1 +/- 15.5, and 48.8 +/- 8.6 for T0, T1, and T2, respectively). Free seminal plasma carnitine concentration was higher in the LM group compared to the HM one. Both pyr...Continue Reading

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Citations

May 7, 2010·Journal of Molecular Histology·Mehmet KanterSule Parlar
Feb 18, 2016·BioMed Research International·Zamira Gibb, Robert J Aitken
Aug 3, 2006·Cell Biochemistry and Function·Dikmen DokmeciYesim Hulya Uz
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Nov 6, 2017·Environmental Science and Pollution Research International·Maurya KhushbooGuruswami Gurusubramanian
Jun 25, 2020·Animals : an Open Access Journal From MDPI·Valentina LongobardiBianca Gasparrini
Aug 18, 2020·Biopreservation and Biobanking·Igor H A V NeryMaria Madalena Pessoa Guerra
Mar 28, 2021·Reproduction in Domestic Animals = Zuchthygiene·Marilena BazzanoAndrea Marchegiani
May 2, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Rabie L Abdel AzizAbdel-Tawab A Y Khalil
Dec 9, 2021·Andrologia·Monique de Albuquerque LagaresRafael Romero Nicolino

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