Effect of Lansoprazole on the Control of the Intragastric pH in a Patient with Short Bowel Syndrome

Internal Medicine
Masato YoshiokaYuzo Yamamoto

Abstract

A 40-year-old man suffered from short bowel syndrome. Since a large amount of intestinal output and watery diarrhea hampered his quality of life, we tried to control the intestinal output by reducing the secretion of gastric acid with lansoprazole. Because the small intestine was only 10 cm in length and effective absorption of oral lansoprazole was doubtful, we monitored his intragastric pH for 24 hours and confirmed that the holding time above pH 3.0 was 14.5 hours (60.4%). He spent his home life eating porridge during the day, and receiving total parenteral nutrition of 1,100 mL/day at night while taking lansoprazole as an oral tablet (30 mg) once a day.

References

Jun 1, 1992·Digestive Diseases and Sciences·M HongoT Toyota
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Sep 1, 1986·Scandinavian Journal of Gastroenterology·O JacobsenS Jarnum
Aug 5, 1998·Alimentary Pharmacology & Therapeutics·W P GeusC B Lamers
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Nov 14, 2008·Current Gastroenterology Reports·Mitchell L Schubert
Jan 17, 2012·Current Problems in Surgery·Jon S ThompsonDavid F Mercer
Jan 28, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Vanessa J Kumpf
Feb 4, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Palle B Jeppesen
Apr 23, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Kristina ChenPalle B Jeppesen

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Citations

Dec 17, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Macie A EnmanDavid P Galloway

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BETA
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