Effect of large fundal varices on changes in gastric mucosal hemodynamics after endoscopic variceal ligation

Endoscopy
C TayamaK Tanikawa

Abstract

BACKGROUNDS AND STUDY AIMS: Effect of endoscopic variceal ligation (EVL) on gastric mucosal hemodynamics would differ in patients with and without large fundal varices. The aim of this study was to test this hypothesis. Twenty-seven patients with cirrhosis and large sized esophageal varices were prospectively studied. There were eight patients with large fundal varices and 19 patients without large fundal varices. Before EVL, gastric mucosal hemodynamics were endoscopically assessed by laser-Doppler velocimetry and reflectance spectrophotometry in the antrum and the corpus. In the reflectance spectrophotometric measurements, gastric mucosal hemoglobin content (IHb) and gastric mucosal oxygen saturation (ISO2) were determined. The severity of portal-hypertensive gastropathy (PHG) was also recorded at the antrum and the corpus. For data analysis, PHG was scored (absent, 0; mild, 1; severe, 2; bleeding, 3). These measurements were repeated after initial (three days after initial session) and repeated (seven days after last session) EVL. At the antrum, neither PHG score nor gastric mucosal hemodynamic parameters were modified after initial and repeated EVL in patients with and without large fundal varices. In addition, no significa...Continue Reading

Citations

Nov 24, 2004·Gastrointestinal Endoscopy·Sri Prakash MisraManisha Gupta
Jul 13, 2013·The Pan African Medical Journal·Mounia LahbabiDafr Allah Benajah
Sep 22, 2001·Clinics in Liver Disease·S K Sarin, S R Agarwal
Oct 30, 1998·Journal of Gastroenterology and Hepatology·A Toyonaga, T Iwao
Apr 7, 2015·Arkhiv patologii·T S SemenovaA G Shertsinger

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