PMID: 3759538Oct 1, 1986Paper

Effect of latency on calculated complication rates

International Journal of Radiation Oncology, Biology, Physics
T E SchultheissD O Dixon

Abstract

Late complications of radiation therapy and other cancer therapies may not always be expressed because of the shortened survival of cancer patients. Methods for estimating the true complication rate must account for censoring of the data. Actuarial methods give the time-dependent probability of remaining free of the injury. However, these methods fail when the last surviving patient develops a complication. This study describes a different method for calculating the corrected complication rate. One advantage is that the method does not produce estimates of 100% for the complication rate that occur using the actuarial method when the last survivor suffers a complication. To use the method presented here, the distribution of latent periods of the injury and the survival function for the patients at risk must be identified.

Citations

Mar 30, 1995·International Journal of Radiation Oncology, Biology, Physics·E L GilletteZ Vujaskovic
May 15, 1995·International Journal of Radiation Oncology, Biology, Physics·L CohenT K Kroc
Aug 30, 1995·International Journal of Radiation Oncology, Biology, Physics·L CohenR C Kennaugh
Jun 15, 1995·International Journal of Radiation Oncology, Biology, Physics·T E SchultheissW R Lee
Jan 1, 1997·International Journal of Radiation Oncology, Biology, Physics·T E SchultheissG E Hanks
Aug 1, 1997·International Journal of Radiation Oncology, Biology, Physics·D Herbert
Mar 15, 2016·International Journal of Radiation Oncology, Biology, Physics·Rainer J KlementMatthias Guckenberger
Mar 5, 2010·International Journal of Radiation Oncology, Biology, Physics·John P KirkpatrickTimothy E Schultheiss
Jan 1, 1989·International Journal of Radiation Oncology, Biology, Physics·L CohenA Lennox
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Feb 5, 2008·International Journal of Radiation Oncology, Biology, Physics·Timothy E Schultheiss
Jul 1, 1989·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·I Turesson
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Oct 12, 2014·International Journal of Radiation Oncology, Biology, Physics·Ankit ModhAbraham J Wu
Aug 1, 1992·The British Journal of Radiology·D J HusbandH M Warenius
Jan 1, 1989·International Journal of Radiation Biology·S M BentzenD O Dixon

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