Effect of long-term exposure to simazine on brain and muscle acetylcholinesterase activity of common carp (Cyprinus carpio)

Environmental Toxicology
A L OropesaFrancisco Soler

Abstract

Several water-contamination incidents with simazine have occurred in the province of Badajoz (Spain), due to its excessive use for controlling weeds in olive trees and vineyards. Simazine residues were also detected in drinking water, increasing public health concern. However, little is known on the effects that low levels of simazine pose to environment organisms. We investigated if residues of simazine in the natural waters would affect brain and muscle acetylcholinesterase activity in common carps captured in areas in which simazine residues were detected at average levels of 4.5 microg/L. Results confirmed depression on brain and muscle acetylcholinesterase activity of 20% and 29%, respectively, in carps inhabiting one of the simazine-contaminated ponds, termed "Molinos de Matachel." To assess the biological significance of this finding, we developed a controlled laboratory study in which carps were exposed to simazine at 45 microg/L (10-fold that of the natural water levels) for 90 days. The results obtained in the field study were not confirmed in our laboratory experiment, since carps did not show evidence or brain or muscle acetylcholinesterase activity depression for the duration of the experiment, and therefore, we ca...Continue Reading

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Citations

Sep 21, 2011·Bulletin of Environmental Contamination and Toxicology·Roberta CattaneoLuis Antonio de Avila
Feb 4, 2012·Environmental Toxicology and Pharmacology·Alzbeta StaraJosef Velisek
Jan 1, 2009·Environmental Toxicology and Pharmacology·Ana-Lourdes OropesaFrancisco Soler
Jan 5, 2011·Journal of Applied Toxicology : JAT·Roberta CattaneoRenato Zanella
Nov 26, 2010·Ecotoxicology and Environmental Safety·Bibiana Silveira MoraesGeovane Boschmann Reimche
Jan 9, 2009·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Ana L OropesaFrancisco Soler

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