Jan 5, 2008

Effect of major cations and pH on the acute toxicity of cadmium to the earthworm Eisenia fetida: implications for the biotic ligand model approach

Archives of Environmental Contamination and Toxicology
Lian-Zhen LiQuan-Ying Wang


The purpose of this study was to characterize the individual effect of different cations (Ca(2+), Mg(2+), Na(+), K(+), and H(+)) on the acute toxicity of Cd to the earthworm Eisenia fetida. Higher activities of the considered cations increased the 48-h LC(50) (expressed as Cd(2+) activities) linearly to different extents in simulated soil solution. The conditional constants for the binding of H(+ )(log K = 5.41), Cd(2+ )(log K = 4.0), Ca(2+ )(log K = 3.35), Mg(2+ )(log K = 2.82), Na(+ )(log K = 1.57), and K(+ )(log K = 2.31) to the biotic ligand (BL) of E. fetida were derived from the toxicity data based on the biotic ligand model (BLM). Furthermore, it was calculated that on average 72% of the BL sites needed to be occupied by Cd(2+) to induce 50% lethal effect. Autovalidation of the model with the results of the test sets showed that 48-h LC(50 )could be predicted within a factor of two.

  • References19
  • Citations14


Mentioned in this Paper

Cadmium Measurement
Lethal Dose 50
Toxicity Tests, Acute
Ligands Activity
Subclass Oligochaeta
Eisenia foetida

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