PMID: 9649083Jul 2, 1998Paper

Effect of maternal carbohydrate metabolism on fetal growth

Obstetrics and Gynecology
A CarusoA M Fulghesu

Abstract

To determine the effect of maternal carbohydrate metabolism and anthropometric characteristics on fetal growth. Eight pregnant women in the third trimester with unexplained fetal growth restriction (FGR) and 11 women with normal pregnancies in the third trimester were evaluated for maternal carbohydrate metabolism, using oral glucose tolerance tests and hyperinsulinemic-euglycemic clamps. These data and maternal anthropometric characteristics subsequently were related to relative birth weight, defined as observed birth weight x 100/50th percentile birth weight. The women with FGR pregnancies were more insulin sensitive than were controls (21.6+/-4.4 versus 16.7+/-4.8 micromol/kg x min, P < .05) and showed reduced insulin and glucose areas under the curve (96,293+/-25,870 versus 145,291+/-49,356 pmol/L, P < .03; 1057.0+/-184.7 versus 1210.1 +/-85.9 mmol/L, P < .05, respectively). No differences were seen in fasting plasma glucose, insulin and human placental lactogen samples, age, height, pregravid weight, weight gain, and parity. In all patients, maternal insulin sensitivity and weight gain correlated well with relative birth weight (r =-.65, P < .002; r=.68, P < .001, respectively). When the same analysis was computed separate...Continue Reading

References

Feb 1, 1990·American Journal of Obstetrics and Gynecology·S FerrazzaniS Mancuso
Oct 16, 1986·The New England Journal of Medicine·L TallarigoR Navalesi
Jan 1, 1969·Obstetrics and Gynecology·A G King
Aug 1, 1995·Obstetrics and Gynecology·B Abrams, S Selvin
May 1, 1995·American Journal of Obstetrics and Gynecology·P M CatalanoS B Amini
May 1, 1995·American Journal of Obstetrics and Gynecology·P M CatalanoS B Amini

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Citations

Jun 1, 2005·Clinics in Perinatology·Barbara Luke
Nov 5, 1999·Obstetrics and Gynecology·E C KiefferA Ventura
Mar 7, 2000·Paediatric and Perinatal Epidemiology·E C Kieffer
Feb 20, 1999·Journal of Women's Health
Mar 29, 2008·Metabolic Syndrome and Related Disorders·Kristine Y Lain, Patrick M Catalano
Mar 17, 2004·Clinical Obstetrics and Gynecology·Barbara Luke
Feb 14, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·I StergiotouF Crispi
May 24, 2011·The Journal of Obstetrics and Gynaecology Research·Giancarlo ParadisiAlessandro Caruso
Mar 1, 2014·Acta Obstetricia Et Gynecologica Scandinavica·Tormod Rogne, Geir W Jacobsen
Dec 20, 2005·Seminars in Perinatology·Barbara Luke
Aug 9, 2005·Early Human Development·Bridget KnightAndrew T Hattersley
Feb 2, 2010·American Journal of Obstetrics and Gynecology·Yi-Hua ChenHorng-Yuan Lou
Jun 10, 2014·American Journal of Obstetrics and Gynecology·Sumudu N SeneviratnePaul L Hofman
Sep 15, 2016·Journal of Diabetes·Dukhabandhu NaikNihal Thomas
Aug 24, 2006·Journal of Lipid Research·A L Magnusson-OlssonT L Powell
Jan 13, 2018·Journal of Women's Health·Hayan KwonYoung-Han Kim
Nov 6, 2009·Obstetrics and Gynecology·Anne L JaquieryJane E Harding
Dec 21, 2011·Obstetrics and Gynecology·Signe N StafneSiv Mørkved
May 24, 2003·Current Diabetes Reports·P M Catalano, J P Kirwan
Feb 15, 2007·American Journal of Physiology. Endocrinology and Metabolism·Anne Liese Magnusson-OlssonTheresa L Powell
Mar 26, 2010·The Journal of Clinical Endocrinology and Metabolism·Sarah A HopkinsPaul L Hofman
Dec 10, 1999·Current Opinion in Clinical Nutrition and Metabolic Care·S C Kalhan, S Devapatla
Aug 14, 2012·Clinical and Experimental Pharmacology & Physiology·Andrew L SiebelBronwyn A Kingwell
Apr 7, 2011·American Journal of Physiology. Endocrinology and Metabolism·Maria Grazia DalfràAnnunziata Lapolla
Jul 1, 2015·Clinical Obstetrics and Gynecology·Barbara Luke
Jul 4, 2021·American Journal of Obstetrics and Gynecology·Darios GetahunKaren J Coleman

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