Effect of maternal-fetal disorders on lung maturation. I. Diabetes mellitus

American Journal of Obstetrics and Gynecology
H E FadelH C Davis

Abstract

Amniotic fluid for fetal lung maturity studies was obtained from 287 healthy and 198 diabetic women. Classes of diabetes were as follows: Class A, 111; Class B, 58; Class C, 13; Class D, 11; Class F, 4; and Class R, 1. The regression lines representing the relationship of amniotic fluid lecithin phosphorus concentration to gestational age at amniocentesis in each of the groups of diabetic patients were not statistically different from those of the control subjects. Each of the diabetic patients was then matched with a control subject of the same race, sex of newborn infant, and gestational age at amniocentesis. The regression lines of the nonhypertensive, hypertensive, and all diabetics were not different from those of their respective matched control subjects. Also there was no difference in the proportion of mature lecithin phosphorus concentrations at different weeks between diabetic and normal women. The absence of a significant influence of diabetes on fetal lung maturation is probably due to improvement in diabetic control resulting in normalization of the fetal metabolic environment.

References

Dec 1, 1985·American Journal of Obstetrics and Gynecology·I S MashiniH A Hadi
Feb 15, 1981·American Journal of Obstetrics and Gynecology·H E FadelE C Abraham

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Citations

Jul 3, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J J PiazzeE V Cosmi
Nov 26, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·I TekesinS Schmidt
Jan 1, 1989·Critical Reviews in Clinical Laboratory Sciences·T Spillman, D B Cotton
Apr 10, 2003·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·O Langer
Mar 23, 2017·The Cochrane Database of Systematic Reviews·Devender RobertsStuart R Dalziel
Oct 1, 1994·Scandinavian Journal of Clinical and Laboratory Investigation·A ZapataJ M Hernández-García

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