Effect of methylphenidate on Stroop Color-Word task performance in children with attention deficit hyperactivity disorder

Psychiatry Research
Daniel D LanglebenG Austin

Abstract

Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric syndrome common in the pediatric population. It is associated with multiple nonspecific deficits on neuropsychological tests of executive function, and a beneficial response to pharmacotherapy with methylphenidate (MPH) and other psychostimulants. The Stroop Color-Word task is used empirically as an aid in diagnosis and treatment monitoring of ADHD; however, data on the sensitivity of the Stroop interference score to the effects of MPH are limited. To address this issue, we studied Stroop performance in a cohort of 18 MPH-treated prepubescent boys with ADHD and six healthy controls on and off MPH treatment conditions. MPH significantly improved performance in both groups, with the ADHD participants consistently displaying worse scores than those of controls both on and off MPH. These results suggest that though the diagnostic value of the Stroop task in ADHD remains controversial, it has heuristic value for monitoring clinical responses to MPH treatment. More research is needed to ascertain the clinical significance of our findings and to replicate this relatively small effect in a larger cohort, to determine whether MPH effects on Stroop performance are spec...Continue Reading

References

Jan 1, 1991·Child Psychiatry and Human Development·J EverettD Michaud
Feb 1, 1980·Journal of Abnormal Psychology·H WeingartnerE D Caine
Mar 24, 1998·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·J H MendelsonJ W Sholar
Jul 3, 1999·Progress in Neuro-psychopharmacology & Biological Psychiatry·M Ernst
Jan 11, 2000·Clinical Pharmacokinetics·H C KimkoD R Abernethy
Jan 22, 2002·Journal of the American Academy of Child and Adolescent Psychiatry·Joel T NiggMarsha D Rappley
Apr 6, 2002·The Clinical Neuropsychologist·L J RapportS R Friedman
Jun 13, 2002·Developmental Neuropsychology·Tim ShalliceRaffaella I Rumiati
Nov 29, 2002·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Julia J Rucklidge, Rosemary Tannock
Mar 11, 2003·Journal of Child and Adolescent Psychopharmacology·Anne-Claude BedardRosemary Tannock
May 28, 2004·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Anouk ScheresJoseph A Sergeant
Feb 1, 2005·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Rosa van MourikJoseph A Sergeant

❮ Previous
Next ❯

Citations

Dec 29, 2009·Journal of Child and Adolescent Psychopharmacology·Mary SolantoRegina Lara
Apr 1, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Katya RubiaEric Taylor
Apr 3, 2007·Journal of Neurology·Yael LeitnerJeffrey M Hausdorff
Oct 27, 2012·Journal of Autism and Developmental Disorders·Nicole PapadopoulosJennifer L McGinley
Apr 6, 2012·Psychiatry Research·Alexandra SebastianOliver Tüscher
Jun 20, 2008·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·D Purper-OuakilP Gorwood
Oct 25, 2011·The International Journal of Neuropsychopharmacology·Li YangYufeng Wang
May 3, 2007·Journal of Integrative Neuroscience·Daniel F HermensLeanne M Williams
Dec 16, 2016·Journal of Child and Adolescent Psychopharmacology·Maria Pia BucciRichard Delorme
May 24, 2012·Journal of Attention Disorders·Rebecca A LangmaidNicole J Rinehart
Mar 9, 2011·Journal of Learning Disabilities·James B HaleNicole Jones
Oct 1, 2019·International Journal of Methods in Psychiatric Research·Ainara Gómez-GastiasoroNatalia Ojeda

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Related Papers

Journal of Child and Adolescent Psychopharmacology
Stephen V FaraoneLarry Seidman
Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Marieke M Lansbergen, J Leon Kenemans
Proceedings of the National Academy of Sciences of the United States of America
C J VaidyaJ D Gabrieli
Journal of Child Psychology and Psychiatry, and Allied Disciplines
Jeffery N EpsteinJulie Spicer
© 2021 Meta ULC. All rights reserved