Effect of metoprolol in reducing myocardial ischemic threshold during exercise and during daily activity

The American Journal of Cardiology
D TzivoniP Brunel

Abstract

In a study of 48 patients with coronary artery disease and evidence of ischemia during exercise and daily life, metoprolol reduced the threshold of myocardial ischemia in a dose-dependent manner. This effect of beta blockers is probably due to increased coronary tone.

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