Effect of Mg(2+) doping on beta-alpha phase transition in tricalcium phosphate (TCP) bioceramics

Acta Biomaterialia
Matteo Frasnelli, Vincenzo M Sglavo

Abstract

The beta to alpha transition in tricalcium phosphate (TCP) bioceramics containing different amount of magnesium was studied in the present work. Mg-doped TCP powder was obtained by solid-state reaction starting from pure calcium carbonate, ammonium phosphate dibasic and magnesium oxide powders. The β to α transformation temperature was identified by dilatometric and thermo-differential analyses. Small pellets produced by uniaxial pressing samples were employed to study the influence of Mg(2+) on the transition kinetic, after sintering at 1550°C and subsequent slow or fast cooling down to room temperature. The evolution of β- and α-TCP crystalline phases during each thermal treatment was determined by X-ray powder diffraction analysis combined with Rietveld method-based software An annealing treatment, suitable to reconvert metastable α phase to the more clinically suitable β phase, was also investigated. It is shown that the presence of magnesium within the TCP lattice strongly influences the kinetic of the β⇆α phase transition, promoting the spontaneous α→β reconversion even upon fast cooling, or slowing down the β→α transition during heating. Similarly, it allows the α→β transformation in TCP sintered components by optimized ...Continue Reading

References

Jul 6, 2000·Journal of Biomedical Materials Research·N RangavittalM Vallet-Regí
Oct 31, 2003·Biomaterials·Hyun-Seung RyuSung-Soo Chung
Sep 14, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·R NarayananK H Kim
Jul 23, 2008·Acta Biomaterialia·Xia LiR Z LeGeros
Sep 26, 2008·Chemical Reviews·Lijun Wang, George H Nancollas
Jun 30, 2011·Acta Biomaterialia·R G Carrodeguas, S De Aza
Dec 6, 2012·Acta Biomaterialia·E Champion

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Citations

Sep 23, 2020·Nanomaterials·Sadaf BatoolManzar Sohail
Jun 3, 2017·Journal of Applied Biomaterials & Functional Materials·Adriana Bigi, Elisa Boanini
Dec 5, 2020·International Journal of Molecular Sciences·Katarzyna SzurkowskaJoanna Kolmas
Mar 4, 2021·Journal of Applied Biomaterials & Functional Materials·Zhen YuanFushuai Yang
Jan 24, 2021·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Rama BallouzeJer Ping Ooi
Jul 7, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Mattia BiesuzVincenzo M Sglavo

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