Effect of mindfulness-based stress reduction on somatic symptoms, distress, mindfulness and spiritual wellbeing in women with breast cancer: Results of a randomized controlled trial

Acta Oncologica
Hanne WürtzenChristoffer Johansen

Abstract

Women with breast cancer experience different symptoms related to surgical or adjuvant therapy. Previous findings and theoretical models of mind-body interactions suggest that psychological wellbeing, i.e. levels of distress, influence the subjective evaluation of symptoms, which influences or determines functioning. The eight-week mindfulness-based stress reduction (MBSR) program significantly reduced anxiety and depression in breast cancer patients in a randomized controlled trial (NCT00990977). In this study we tested the effect of MBSR on the burden of breast cancer related somatic symptoms, distress, mindfulness and spiritual wellbeing and evaluated possible effect modification by adjuvant therapy and baseline levels of, distress, mindfulness and spiritual wellbeing. A population-based sample of 336 women Danish women operated for breast cancer stages I-III were randomized to MBSR or usual care and were followed up for somatic symptoms, distress, mindfulness skills and spiritual wellbeing post-intervention and after six and 12 months. Effect was tested by general linear regression models post-intervention, and after six and 12 months follow-up and by mixed effects models for repeated measures of continuous outcomes. Effect...Continue Reading

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Citations

Apr 25, 2015·Acta Oncologica·Christoffer Johansen, Susanne Oksbjerg Dalton
Sep 1, 2015·Current Breast Cancer Reports·Ad A KapteinKoos J M van der Hoeven
May 27, 2016·The Cochrane Database of Systematic Reviews·Rachael PowellMarie Johnston
Jan 10, 2019·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Anna G LarsonErin S Costanzo
Mar 28, 2019·The Cochrane Database of Systematic Reviews·Lisa K SchellNicole Skoetz
Dec 14, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·N G XunlinPiyanee Klainin-Yobas
Jul 12, 2017·Psychology & Health·Cynthia WanCatherine Bielajew
Apr 21, 2019·Breast Cancer Research and Treatment·Narjes BahriAbdoljavad Khajavi
Nov 30, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Qiuxiang ZhangYaning Zheng
Jan 12, 2021·Asia-Pacific Journal of Oncology Nursing·Srisuda NgamkhamEllen Lavoie Smith

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