Effect of mode of delivery in nulliparous women on neonatal intracranial injury

The New England Journal of Medicine
D TownerW M Gilbert

Abstract

Infants delivered by vacuum extraction or other operative techniques may be more likely to sustain major injuries than those delivered spontaneously, but the extent of the risk is unknown. From a California data base, we identified 583,340 live-born singleton infants born to nulliparous women between 1992 and 1994 and weighing between 2500 and 4000 g. One third of the infants were delivered by operative techniques. We evaluated the relation between the mode of delivery and morbidity in the infants. Intracranial hemorrhage occurred in 1 of 860 infants delivered by vacuum extraction, 1 of 664 delivered with the use of forceps, 1 of 907 delivered by cesarean section during labor, 1 of 2750 delivered by cesarean section with no labor, and 1 of 1900 delivered spontaneously. As compared with the infants delivered spontaneously, those delivered by vacuum extraction had a significantly higher rate of subdural or cerebral hemorrhage (odds ratio, 2.7; 95 percent confidence interval, 1.9 to 3.9), as did the infants delivered with the use of forceps (odds ratio, 3.4; 95 percent confidence interval, 1.9 to 5.9) or cesarean section during labor (odds ratio, 2.5; 95 percent confidence interval, 1.8 to 3.4), but the rate of subdural or cerebra...Continue Reading

Associated Clinical Trials

Nov 25, 2013·Tullio Ghi

References

Jul 24, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C LoghisP A Zourlas
Aug 1, 1990·British Journal of Obstetrics and Gynaecology·G J HofmeyrM J Turner
May 1, 1989·British Journal of Obstetrics and Gynaecology·R JohansonP Jones
Jun 1, 1993·British Journal of Obstetrics and Gynaecology·R B JohansonP M O'Brien
Jul 1, 1996·British Journal of Obstetrics and Gynaecology·J O Drife
Jun 1, 1996·Journal of Paediatrics and Child Health·A Vacca
Jun 1, 1996·Journal of Paediatrics and Child Health·L M ChadwickJ J Kurinczuk
Oct 1, 1996·Obstetrics and Gynecology·K Hickey, P McKenna
Feb 1, 1997·Obstetrics and Gynecology·F Y Teng, J W Sayre
Jun 1, 1997·Neurosurgery·R G PerrinR P Humphreys
May 20, 1998·American Journal of Public Health·P BravemanR Williams
Sep 10, 1998·American Journal of Obstetrics and Gynecology·T S NesbittB Herrchen

❮ Previous
Next ❯

Citations

Jun 16, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Judith Littleford
May 19, 2009·Pediatric Radiology·Handan Cakmakci
Jan 1, 2009·Archives of Gynecology and Obstetrics·Nir MelamedAvi Ben-Haroush
Sep 8, 2010·Archives of Gynecology and Obstetrics·Hamisu M SalihuPhillip J Marty
Dec 17, 2009·Forensic Science, Medicine, and Pathology·Gary L Hedlund, Lori D Frasier
Jan 17, 2014·Journal of Obstetrics and Gynaecology of India·Sanchila TalukdarMichael Geary
Jan 17, 2014·Journal of Obstetrics and Gynaecology of India·Uri Erlik, Igal Wolman
Dec 13, 2005·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Leslie A Parker
Feb 7, 2006·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Leslie A Parker
Sep 4, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Mark P HehirRhona Mahony
Jun 12, 2003·Obstetrics and Gynecology·Tong LiLakota Kruse
Dec 16, 2003·Obstetrics and Gynecology·William M GilbertBeate Danielsen
May 3, 2001·Lancet·M Miller
Mar 11, 2004·Blood Reviews·Elizabeth A Chalmers
Mar 22, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Oscar SadanMarek Glezerman
Apr 6, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Y C CheongF M Fairlie
Sep 21, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·A KentB Paes
Jul 15, 2009·Journal de gynécologie, obstétrique et biologie de la reproduction·L SentilhesA Fournié
Jul 15, 2009·Journal de gynécologie, obstétrique et biologie de la reproduction·J-P SchaalP Hoffman
Jul 15, 2009·Journal de gynécologie, obstétrique et biologie de la reproduction·O Baud
Jun 18, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·Karl S Oláh
Jun 18, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·Catalin S BuhimschiCarl P Weiner
Apr 18, 2003·BJOG : an International Journal of Obstetrics and Gynaecology·R Indusekhar, Karl S Oláh
Jun 12, 2003·BJOG : an International Journal of Obstetrics and Gynaecology·Deirdre J MurphyRebecca Swingler
May 24, 2001·Journal of Midwifery & Women's Health·M SimpsonK Wade
Feb 13, 2001·British Journal of Haematology·R Kulkarni, J Lusher
Mar 17, 2001·Birth·R K Demott
Dec 2, 1999·The New England Journal of Medicine·T J Benedetti
Mar 25, 2000·The New England Journal of Medicine·R Nuss, W E Hathaway
Jan 24, 2003·The New England Journal of Medicine·Holger K EltzschigWilliam R Camann
Mar 7, 2003·The New England Journal of Medicine·Howard Minkoff, Frank A Chervenak
Sep 24, 2011·Journal of Neurotrauma·P David AdelsonUNKNOWN Pediatric TBI Demographics and Clinical Assessment Working Group
Dec 29, 2000·Current Opinion in Obstetrics & Gynecology·J P O'GradyS S Patel
Nov 1, 2001·Clinical Obstetrics and Gynecology·M T November
Nov 17, 2001·Obstetrical & Gynecological Survey·P Miksovsky, W J Watson
Feb 8, 2002·Obstetrical & Gynecological Survey·W Benson Harer
Apr 8, 2003·Journal of Pediatric Hematology/oncology·Matthew AbelMargaret Masterson
Apr 8, 2006·Current Opinion in Obstetrics & Gynecology·Stergios K Doumouchtsis, Sabaratnam Arulkumaran
Sep 30, 2003·Obstetrical & Gynecological Survey·Dhiraj Uchil, Sabaratnam Arulkumaran
Jul 28, 2004·Obstetrical & Gynecological Survey·Joseph R WaxJacquelyn Blackstone
May 17, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Roland HaaseStefan Burdach
Jan 20, 2007·Southern Medical Journal·Catherine Matthews NicholsJamie Jennell
Nov 23, 2011·Obstetrics and Gynecology·Erika F WernerHeather S Lipkind
Sep 1, 2007·Clinical Obstetrics and Gynecology·Dena R Towner, Mary C Ciotti
Jul 14, 2000·BMJ : British Medical Journal·D Carnall

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.