PMID: 6980237Aug 1, 1982Paper

Effect of moderate malnutrition on immediate hypersensitivity and immunoglobulin E levels in asthmatic children

The Journal of Allergy and Clinical Immunology
M A ReyesD N McMurray

Abstract

Dermal reactions and IgE levels were compared in 51 asthmatic Colombian children identified on the basis of anthropometric measurements as nutritionally normal (25) or mildly (16) or moderately (10) undernourished. Twenty-five nonatopic children served as controls. Total serum IgE concentrations were significantly elevated in the asthmatic group as a whole. Moderately malnourished (grade II) asthmatic children had more than twice as much serum IgE as normal or mildly malnourished (grade I) asthmatic subjects and seven times more than nonatopic children. Intestinal parasitism did not appear to contribute to these differences in IgE levels. Serum levels of IgA and IgD were similarly elevated in grade II asthmatics. Concentrations of serum IgG, IgM, and C3 and C4 complement were unaffected by nutritional or allergic status. Eosinophilia in nasal mucus was significantly reduced in grade I and grade II malnourished asthmatic children. Among asthmatics, the most frequent dermal reactions were to mite antigens (96%), house dust (67%), and grass pollens (35%). Significant levels of specific IgE were detected by the RAST to two species of mites in nearly all atopic children. There was no apparent influence of nutritional status on the d...Continue Reading

References

Jan 1, 1978·Immunological Reviews·R H Buckley, W G Becker
Jul 1, 1979·The Journal of Asthma Research·L D CharletM A Reyes
Sep 1, 1974·Archives of Disease in Childhood·J K Sarsfield
May 4, 1972·The New England Journal of Medicine·J A PhillsL Perelmutter

❮ Previous
Next ❯

Citations

Sep 1, 1996·Journal of Clinical Epidemiology·T ShirakawaK Morimoto
Jun 1, 1994·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C VidalV Cuervas-Mons
Sep 14, 2004·Revista do Hospital das Clínicas·Joel FaintuchJoaquim José Gama-Rodrigues
Mar 20, 2008·Environmental Entomology·David A Jenkins, Ricardo Goenaga

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Virchows Archiv. A, Pathological Anatomy and Histopathology
K A Bardadin, P J Scheuer
International Archives of Allergy and Applied Immunology
H Kimata, A Saxon
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
A LernerE Lebenthal
The Journal of Allergy and Clinical Immunology
G Y MinukB J Green
© 2021 Meta ULC. All rights reserved